跳至主要内容
临床试验/NCT06120985
NCT06120985已完成不适用

Expanding Safe Water Access to Improve Health Outcomes in Rural Appalachia: A Pilot Water Treatment Intervention Trial in Virginia & Tennessee

Virginia Polytechnic Institute and State University3 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2023年11月19日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
76
试验地点
3
主要终点
E. coli detection in drinking water

研究概览

简要总结

Consumption of unsafe drinking water is associated with a substantial burden of disease globally. In the USA, the burden of disease associated with consumption of contaminated drinking water from non-regulated private wells and springs in rural areas is relatively understudied and unclear. For some lower-income households in rural areas of the USA without access to reliably safe drinking water, point-of-use treatment with relatively low-cost pitcher filters could help to reduce exposures to contaminated water and associated adverse health outcomes. This pilot randomized controlled intervention trial will provide information and data on water quality and contamination exposures, associated health outcomes, and the adoption potential of point-of-use water filters in rural areas of Virginia and Tennessee.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
6 Months 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The household does not have utility-supplied water at the time of enrollment,
  • The household is considered to be "low-income" (based on federally defined income limits),
  • The household is in one of the selected study counties in TN or VA.

排除标准

  • None (no exclusion criterion based on gender, race, ethnicity, language, or literacy).

研究组 & 干预措施

Treatment

Active Comparator

Households randomized to the treatment group will be provided countertop pitcher water filters

干预措施: Countertop pitcher water filter (Device)

Control

No Intervention

Households randomized to the control group will be provided water filters at the completion of the study

结局指标

主要结局

E. coli detection in drinking water

时间窗: 12 months

Proportion of households with E. coli (indicator of fecal contamination) detected in drinking water samples

Heavy metals or other contaminants exceeding EPA MCL

时间窗: 12 months

Proportion of households with contaminants detected in drinking water at concentrations exceeding the US Environmental Protection Agency (EPA) Safe Drinking Water Act (SDWA) Maximum Contaminant Levels (MCL)

次要结局

  • Pathogen infection(12 months)
  • Gastrointestinal illness(12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alasdair Cohen

Assistant Professor of Environmental Epidemiology

Virginia Polytechnic Institute and State University

研究点 (3)

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