Effect of Avocado Honey (Apis Mellifera) on Anthropometric and Biochemical Parameters in Healthy Subjects: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Subject numbers that experienced change of LDL-cholesterol levels (mg/dL) post-intake of 25 g/day honey
研究概览
简要总结
Thirteen healthy subjects (5 males; 8 females) ages 25-50 years, with BMI (body mass index): <25 kg/m2 completed the study. The participants were selected randomly, either the control group (n= 7) or honey group (n= 6). Subjects of honey group consumed 25 g of honey each day for 4 weeks.
详细描述
18 healthy participants (body mass index [BMI] <25 kg/m2) between 25-50 years of age were recruited, of which 13 subjects (male [n=5]) and female [n=8]) completed the study. The participants were allocated randomly either control group (n= 7) or honey group (n= 6). Subjects of honey group consumed 25 g of honey each day for 4 weeks. Participants of both groups did not undergo a special diet regimen, drug therapy, or change in their lifestyle, such as physical exercise, during the period of study. A 3- day food record including two weekdays and one weekend day was used to assess the habitual food intake of the participants prior to initiation of the trial and repeated each week of intervention. Also, dietary intake was calculated using the database Food Processor® (Version. 10.3.0.), including nutritional information of Mexican foods when they weren't on the list.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages 25-50 years,
- •BMI (body mass index): under 25 kg per m2.
排除标准
- •Not smoker
- •Not have an allergy to honey
- •Not pregnant,
- •Not been previously diagnosed any disease resulting in metabolic disorders
- •Not chronically use medications known to affect metabolism
- •Not participate in greater than 3 hours of structured exercise per week.
- •Female participants that used some kind of contraceptives
结局指标
主要结局
Subject numbers that experienced change of LDL-cholesterol levels (mg/dL) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced a change of glucose level (mg/dL) post-intake of 25 g/day of honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of body fat (%) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of BMI (weight (kg)/height (m)2) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of body weight (kg) post-intake of 25 g/day honey.
时间窗: Frame: from the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of waist circumference (cm) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of triglycerides levels (mg/dL) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of total cholesterol levels (mg/dL) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of HDL-cholesterol levels (mg/dL) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of waist-hip ratio post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
Subject numbers that experienced change of hip circumference (cm) post-intake of 25 g/day honey
时间窗: From the start of treatment (baseline) until 4 weeks
次要结局
未报告次要终点
研究者
Marcelo Hernández-Salazar
PhD. Marcelo Hernández-Salazar, Principal investigator
Universidad Autonoma de Nuevo Leon