The Effect of Glasgow Coma Scales on General Anesthesia in Neurosurgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 主要终点
- BIS, Consumption of the inhalation agents
研究概览
简要总结
The study evaluates the general anesthesia management with BIS monitorization in terms of hemodynamic stability, drug concentrations and drug consumption in patients who underwent surgery due to intracranial pathology and who were divided in three different GCS groups.
详细描述
BIS monitoring is mostly used for anesthesia depth and sedation level follow-up, however it can also be used for monitoring consciousness after resuscitation of cases with acute brain injury and cardiac arrest. It is not always possible to monitor and objectively measure the changes in the level of consciousness in clinical practice. Therefore, device-based methods have been introduced in monitoring the state of consciousness. Bispectral index (BIS) monitoring may be preferred in follow up of the state of consciousness in critical patients such as those with acute brain injury, in terms of ease of use, ability to obtain numerical results and continuous monitoring. BIS monitoring is mostly used for follow up of anesthesia depth and sedation level, while it can also be applied for monitoring state of consciousness following resuscitation in cases with acute brain injury and cardiac arrest.In this study, we aimed to investigate general anesthesia management performed by bispectral index monitoring in patients who underwent surgery due to intracranial pathology and with different Glasgow Coma Scales.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 and 65 years
- •ASA II-III
- •intracranial surgery
排除标准
- •Patients with additional disease (electrolyte impairment, uremia, etc.),
- •liver and renal failure affecting consciousness level other than intracranial pathology
研究组 & 干预措施
Group I=13-15 mildly injured
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery. use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group I (n=15)=13-15 mildly injured
干预措施: Bispectral index (BIS) monitoring (Device)
Group I=13-15 mildly injured
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery. use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group I (n=15)=13-15 mildly injured
干预措施: Sevoflurane (Drug)
Group 2 =9-12 moderately damaged
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery.use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group 2 (n=15)=9-12 moderately damaged
干预措施: Bispectral index (BIS) monitoring (Device)
Group 2 =9-12 moderately damaged
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery.use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group 2 (n=15)=9-12 moderately damaged
干预措施: Sevoflurane (Drug)
Group 3=3-8 severely damaged.
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery. use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group 3 (n=15)=3-8 severely damaged.
干预措施: Bispectral index (BIS) monitoring (Device)
Group 3=3-8 severely damaged.
Patients were divided into 3 groups according to the Glasgow Coma Scores calculated before surgery. use of anesthetic agent were recorded during bispectral index (BIS) monitoring and anesthesia application. we used sevoflurane drug intraoperative.
Group 3 (n=15)=3-8 severely damaged.
干预措施: Sevoflurane (Drug)
结局指标
主要结局
BIS, Consumption of the inhalation agents
时间窗: 200 minutes
Preoperative, intraoperative and postoperative BIS values were recorded. The total amount of opioid consumed was recorded from the infusion pump.
次要结局
未报告次要终点
研究者
Sevtap Hekimoglu Sahin
Director, clinical research
Trakya University