The Effect of Training on Oxidative Stress in Patients With Osteoarthritis of the Knee. A Study of the Effects of Supervised Exercise Therapy on Oxidative Stress.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- NRPS Pain score
研究概览
简要总结
A six week patient study that intends to prove that training helps improve the life of people with osteoatritis of the knee.
It looks at pain and function in daily life and markers in the blood that show stress at a cell level.
详细描述
In this study you will be part of a group one that receives 6 weeks of training (2 sessions per week) or you are part of group two that will exercise by walking 6000 steps per day.
To investigate the effect of the training and walking, there will be an first screening of your capillary blood (by use of a few drops of blood from your finger), and you will be asked to fill in some questionnaires about your symptoms, that will include a painscore and a questionair on your specific complaints. These test will be retaken at the end of your 6 weeks of training.
The study is focussed to benefit you by strengthening the muscles around your knee and improving your overall fitness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed Knee osteoartritis in one or both knees
排除标准
- •not able to walk 6000 steps
- •not able to participate in the training
研究组 & 干预措施
supervised training
the patient will recieve 6 weeks of 2 supevised trainings per week as an outpatient
干预措施: supervised training (Other)
walking
the patient will walk 6000 steps per day for the duration of 6 weeks
干预措施: daily walking (Other)
结局指标
主要结局
NRPS Pain score
时间窗: 6 weeks
numeric pain rating scale
PSPF
时间窗: 6 weeks
Patient Specific Functional Scale
oxidative stress bloodmarkers
时间窗: 6 weeks
d-Roms fast test
次要结局
未报告次要终点
研究者
Mariette Boshuis
Physical and Manual therapist
Vrije Universiteit Brussel