NCT07728812尚未招募不适用
Pragmatic Trial to Study the Cost-Effectiveness of MyPhenome-RX Test to Guide Anti-Obesity Pharmacotherapy (PhenoRX Pragmatic Trial)
Phenomix Sciences0 个研究点目标入组 424 人开始时间: 2026年9月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 424
- 主要终点
- Total Body Weight Loss (TBWL) at 6 Months %
研究概览
简要总结
A pragmatic, randomized, parallel-arm, controlled study of weight loss outcomes using AOMs guided by MyPhenome test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults - age 18 or older
- •obesity (BMI ≥ 30 kg/m2) without obesity related diseases (ORDs). Or obesity (BMI ≥ 27 kg/m2) with obesity related diseases (ORDs).
- •Mayo Clinic employee or dependent
- •Referred to Community Internal Medicine Weight Management Program
排除标准
- •Pregnancy or currently breast feeding.
- •No contraindications to the weight loss medications: Phentermine-Topiramate Extended Release (Qsymia®); Oral naltrexone extended-release/bupropion extended-release (NBSR; Contrave®, Mysimba™); Liraglutide (Saxenda®), Semaglutide (Wegovy®), and Tirzepatide (Zepbound®).
结局指标
主要结局
Total Body Weight Loss (TBWL) at 6 Months %
时间窗: 6-Months
TWBL% at 6 months
次要结局
- TBWL% at 3 Months(3-months)
- TBWL% at 9 Months(9-Months)
- TBWL% at 12 Months(12-Months)
- TBWL% at 18 Months(18-Months)
- TBWL% at 24 Months(24-Months)
- Degree of Treatment Response(6-Months)
- Cost of Treatment(3, 6, 9, 12, 18, 24 Months)
- Cost-Effectiveness(3, 6, 9, 12, 18, 24 Months)
- Patient Satisfaction(3, 6, 9, 12, 18, 24 Months)
研究者
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