A study on association of inflammatory ,genetic and epigenetic markers with Kellgren Lawrence grading in post traumatic osteoarthritis of knee
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- We can initiate treatment and screening procedures in handling osteoarthritis subsequent to trauma
研究概览
简要总结
The study participants are inducted into the study after getting written informed consent. They are identified by the consultants in the departments of Arthroscopy and Sports medicine. Individuals in the age group of 20-50 years who give history of injury to the knee joints in less than 3 months are included. All the participants are subjected to clinical examination, objective pain scoring, standard knee outcome score visual-analogue scale (VAS) and WOMAC .X ray will be taken .Blood and urine samples will be collected.The samples will be analysed for biomarkers .Statistical analysis will be done .
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •H/O Knee injury within 3 months.
排除标准
- •History auto immune diseases Any ohter chronic medical ilness Post menopausal women H/O Viscosupplementaion or vit D.
结局指标
主要结局
We can initiate treatment and screening procedures in handling osteoarthritis subsequent to trauma
时间窗: Baseline,6 months and 12 months
次要结局
- Normal joint or OA joint(12 months)
研究者
Keerthy Rethinam M
Sri Ramachandra Institute of higher education and research