Trajectoires Individuelles de Consommation de Cannabis en Situation Habituelle et Observations de Leurs Modalités en Contexte Écologique
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Cannabis use patterns
研究概览
简要总结
The purpose of this study is to identify and characterize patterns of non-therapeutic cannabis consumption and their variation in time in regular/daily users aged 18-24 years using a multi-factor approach (frequency of use, product types, cannabinoid dosages) over a two-year period.
详细描述
Changes in the legal status of cannabis in Canada have highlighted the need for knowledge about the substance and its effects at individual, population and societal levels. In Quebec, in the past year, one in four cannabis users reported weekly use, and around 15% reported daily use. More specifically, young people between the ages of 18 and 24 account for the largest proportion of this consumption, representing a large proportion of these regular to daily users. Little information is currently available about the correlates, evolution and effects of regular, daily cannabis use in this age group, despite the fact that it is the most widely used in the province.
Such comprehensive longitudinal data on consumption dynamics within this population is crucial for our understanding of whether and how cannabis use trajectories vary over time, characterizing the health and social consequences of cannabis consumption at this critical stage in human development, and ultimately providing evidence for the development of strategies to prevent and mitigate potential harms to this specific population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 24 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 24 years of age;
- •Cannabis use frequency of at least 1 day/week in the past three months;
- •Ability to speak and read French or English;
- •willingness to comply with all study procedures;
- •access to a mobile phone.
排除标准
- •Planned extended absence during study period (e.g. pending legal action, surgery, incarceration, inpatient residential program) which, in the opinion of the research staff, might prevent completion of the study;
- •Current or anticipated treatment for cannabis use disorder, confirmed via self-report;
- •Medical document authorizing the use of cannabis for medical purposes;
- •Participation in clinical studies or undergoing other investigational procedures involving cannabis or cannabinoids administration.
结局指标
主要结局
Cannabis use patterns
时间窗: Baseline
Primary outcome measures of this study are specific assessments of cannabis use patterns, measured at baseline and daily using the mobile app. Primary outcome assessments related to cannabis use patterns will be tracked daily, taking advantage of a short but detailed series of questions taking approximately 1-5 minutes to answer, depending on the number of consumption events during the day. Participants will be advised to provide information even during non-consumption days, which in these cases will be limited to their general appreciation of the day, in addition to the fact that they did not consume that day. Participants will be able to retrospectively enter daily cannabis consumption data up to a maximum of seven days in the past, to minimize recall bias.
Trajectories of consumption patterns over time_Route of administration
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will use weekly reports on participants' habits surrounding cannabis use in the form of logbook entries, covering the route of administration for each product. This information will be collected for each consumption session during a use day.
Trajectories of consumption patterns over time_product type
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will use weekly reports on participants' habits surrounding cannabis use in the form of logbook entries, covering the product type for each product. This information will be collected for each consumption session during a use day.
Trajectories of consumption patterns over time_THC constituent (%)
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will use weekly reports on participants' habits surrounding cannabis use in the form of logbook entries, covering the THC constituent (%) for each product. This information will be collected for each consumption session during a use day.
Trajectories of consumption patterns over time_CBD constituent (%)
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will use weekly reports on participants' habits surrounding cannabis use in the form of logbook entries, covering the CBD constituent (%) for each product. This information will be collected for each consumption session during a use day.
Trajectories of consumption patterns over time_amount per use
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will use weekly reports on participants' habits surrounding cannabis use in the form of logbook entries, covering the amount per use for each product. This information will be collected for each consumption session during a use day.
Trajectories of consumption patterns over time_supply source
时间窗: From baseline (Day 1) up to two year (Day 730)
The investigators will also capture information on supply source (choices are: cultivated by me or for me, family member or friend or acquaintance, SQDC, legal source from another province, health Canada licensed producer, illegal market) for each product used in the logbook.
次要结局
- Socio-demographic and behavioral determinants(At Weeks 16, 32, 48, 64 and 96)