A study of emotional responsiveness and apathy in Parkinson*s disease - study of emotion and apathy in PD

niversiteit Maastricht0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Inclusion criteria for PD patients are:
•-Idiopathic Parkinson*s disease according to the Queen Square Brain Bank criteria (De Rijk, Rocca et al, 1997).
•-The use of a stable dose of antiparkinsonian medication.
•-Signed informed consent;Inclusion criteria for healthy controls are:
•-signed informed consent

•Exclusion criteria for PD patients are:
•-patients with other neurodegenerative disorders other than PD
•-Major Depressive Disorder as defined by the criteria of the fourth edition of the Diagnostic and Statistical Manual (DSM-IV) of the American Psychiatric Association (APA) (American Psychiatric Association 1994).
•-cognitive deterioration operationalised as a score of <26 on the Mini Mental State Examination (MMSE) (Folstein, Folstein et al. 1975) or fulfilling diagnostic criteria for Parkinson*s Disease Dementia (PDD) (Dubois, Burn et al. 2007).
•-use of psychopharmacological medication, with the exception of benzodiazepines
•-abuse of alcohol and/or drugs
•-exclusion criteria for MRI scanning;Exclusion criteria for healthy controls are:
•-neurodegenerative disorders
•-Major Depressive Disorder as defined by the criteria of the fourth edition of the Diagnostic and Statistical Manual (DSM-IV) of the American Psychiatric Association (APA) (American Psychiatric Association 1994).
•-cognitive deterioration operationalised as a score of <26 on the Mini Mental State Examination (MMSE) (Folstein, Folstein et al. 1975) or fulfilling diagnostic criteria for Parkinson*s Disease Dementia (PDD) (Dubois, Burn et al. 2007).
•-use of psychopharmacological medication, with the exception of benzodiazepines
•-abuse of alcohol and/or drugs

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