NCT07603128招募中不适用
Prospective Validation of a Risk Prediction Model for MDRGNB Infection: A Multicenter Real-World Prospective Study
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School11 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2026年5月22日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 11
研究概览
简要总结
This prospective multicenter validation study aimed to evaluate the predictive performance of a previously developed model for MDRGNB infection in ICU patients.
详细描述
Adult ICU patients were prospectively and consecutively enrolled across 11 research centers. MDRGNB infection risk predictions were generated within 24 hours of ICU admission using routinely available clinical data. Without interfering with clinical decision-making, the study assessed the discrimination, calibration, and clinical net benefit of the previously developed MDRGNB infection risk prediction model in real-world practice, applying the predefined threshold of 0.318.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years;
- •ICU stay ≥48 hours;
- •At least one clinical microbiological specimen collected and submitted for testing within 48 hours of ICU admission, with the first submission time designated as the index time;
- •Core predictive variables of the model extractable from electronic medical records or laboratory information systems.
排除标准
- •For patients with multiple ICU admissions, only the first ICU stay was retained;
- •Missing or indeterminate primary outcome;
- •Missing key predictive variables that could not be handled according to prespecified rules.
研究者
Chen Dayu
Pharmacist in Charge
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
研究点 (11)
Loading locations...
相似试验
招募中
不适用
Risk Factors and Predictive Model for Inflammatory Polyps in Ureteral StonesUreteral CalculiNCT07559721The First Hospital of Jilin University779
招募中
不适用
Prospective Validation of an AI Model for Predicting Liver Metastasis in Colorectal CancerNCT07392567Tongji Hospital160
招募中
不适用
Adult Disease Risk Prediction Using Wearables, Hearing, and Health DataChronic DiseaseRisk AssessmentNCT07541547National Health Research Institutes, Taiwan1,500
已完成
不适用
Derivation and Validation of the Risk Evaluation Score for Pneumonia Involving Resistant Entities (RESPIRE)PneumoniaNCT07425561Azienda Ospedaliero-Universitaria Careggi300
招募中
不适用
Gestational Lifestyle & Outcomes WellnessGDMNCT07263412The First Affiliated Hospital with Nanjing Medical University1,000