JPRN-UMIN000030984招募中1 期
Phase I study of piggyBac transposon mediated chimeric antigen receptor gene modified T cells for CD19 positive acute lymphoblastic leukemia - piggyBac transposon mediated chimeric antigen receptor gene modified T cells for CD19 positive acute lymphoblastic leukemia
agoya University0 个研究点目标入组 12 人开始时间: 2018年1月25日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 1years-old 至 60years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) predonisolone use >=0.5 mg/kg 2) BM blast >=20% 3) CNS-3 4) isolated extramedullary leukemia 5) severe or uncontrollable infection 6) severe or uncontrollable GVHD 7) severe or uncontrollable heart failure 8) previous use of CAR-T therapy 9) previous use of CD3/CD19 bispesific antibody 10) Psychoses 11) History of allergic reaction to albumin 12) History of allergic reaction to mouse derived protein
研究者
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