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临床试验/NCT04409496
NCT04409496已完成不适用

Chat-based Instant Messaging Support for Preventing Smoking Relapse in the Context of COVID-19 Outbreak: a Pilot Randomised Clinical Trial

The University of Hong Kong1 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2020年6月2日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
108
试验地点
1
主要终点
Biochemically-validated tobacco abstinence

研究概览

简要总结

This pilot trial aims to evaluate the effectiveness of chat-based instant messaging support in preventing smoking relapse in recent tobacco abstainers.

详细描述

Smoking cessation is one of the most cost-effective health interventions, which can add up to 10 years of life expectancy (Jha et al., 2013). However, it is very difficult to quit smoking because of the addictive effect of nicotine presents in tobacco products, and smokers typically make multiple attempts before successfully quit smoking. Providing evidence-based treatment could substantially increase the chance of successful quitting.

The Coronavirus Disease 2019 (COVID-19) provided new opportunities and challenges in promoting smoking cessation. A growing literature has shown that smoking is linked to poor progression of COVID-19 (Patanavanich & Glantz, 2020), which can be a new warning for motivating smokers to quit smoking. However, social distancing measures and increased stress and anxiety related to fear of contracting COVID-19 may increase the risk of smoking relapse in people who recently quit smoking (Patwardhan, 2020). There are also misinformation or unproven claims that smoking can protect against COVID-19. The social distancing measures also become a barrier for smokers who are interested in quitting to receive treatment from smoking cessation clinics. Therefore, implementing new interventions that can address the challenges in the context of the COVID-19 pandemic is needed.

Advance in mobile technologies provides a new avenue for delivering smoking cessation support. A qualitative interview of 21 current smokers in Hong Kong has found that mobile instant messaging app (e.g., WhatsApp) is an acceptable and feasible platform for providing chat support for smoking cessation (Luk et al., 2019). Chat-based support allows a registered nurse or trained counsellor to interact with a smoker individually through mobile instant messaging apps (e.g., WhatsApp and WeChat) and provide real-time, continuous, and personalized smoking cessation information and advice. A randomised trial of 1185 smokers found that the chat-based intervention integrated with brief intervention was effective in increasing smoking cessation (Wang et al., 2019). The trial also provided initial evidence that the intervention can be delivered as a stand-alone treatment or in combination with use of existing cessation treatment, to increase the chance of successful quitting. This study aims to adapt the chat intervention for smoking relapse prevention and evaluate its feasibility and effectiveness in recent tobacco abstainers enrolled in a clinic-based smoking cessation service in Hong Kong.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Hong Kong residents aged 18 years or older
  • •Enrolled in a smoking cessation programme under Tung Wah Group of Hospitals Integrated Centre on Smoking Cessation
  • •Daily tobacco use before service intake
  • •Not using any tobacco product for 3 to 30 days
  • •Own a mobile phone with a mobile instant messaging app (WhatsApp or WeChat) installed
  • •Able to communicate in Chinese (Cantonese or Mandarin)

排除标准

  • •Subjects with communication barriers owing to physical or cognitive conditions will be excluded.

研究组 & 干预措施

Intervention group

Experimental

Chat-based instant messaging support + Self-help booklet

干预措施: Chat-based instant messaging support (Behavioral)

Intervention group

Experimental

Chat-based instant messaging support + Self-help booklet

干预措施: Self-help booklet (Behavioral)

Control group

Active Comparator

SMS message support + Self-help booklet

干预措施: SMS message support (Behavioral)

Control group

Active Comparator

SMS message support + Self-help booklet

干预措施: Self-help booklet (Behavioral)

结局指标

主要结局

Biochemically-validated tobacco abstinence

时间窗: Assessed at 6 months after randomisation

Defined by an exhaled carbon monoxide level of 3 parts per million or below

次要结局

  • Self-reported 7-day point-prevalence tobacco abstinence(Assessed at 6 months after randomisation)
  • Self-reported relapse rate(Assessed at 6 months after randomisation)
  • Self-reported 6-month prolonged tobacco abstinence(Assessed at 6 months after randomisation)
  • Self-reported 7-day point-prevalence tobacco abstinence(Assessed at 3 months after randomisation)
  • Self-reported relapse rate(Assessed at 3 months after randomisation)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tzu-Tsun Luk

Research Assistant

The University of Hong Kong

研究点 (1)

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