Evaluation of the Effect of Non-Surgical Periodontal Treatment on Clinical Periodontal Status With Oral Health Impact Profile (OHIP-14) in Patients With Hemophilia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 146
- 试验地点
- 1
- 主要终点
- Oral Health-Related Quality of Life (OHIP-14) Score
研究概览
简要总结
This study aimed to evaluate the effect of non-surgical periodontal treatment (NSPT) on oral health-related quality of life in patients with hemophilia using the Oral Health Impact Profile-14 (OHIP-14) questionnaire. In addition, clinical periodontal parameters and demographic characteristics before and after NSPT were assessed and compared with systemically healthy individuals. A total of 71 patients with hemophilia (60 with Hemophilia A and 11 with Hemophilia B) and 75 healthy individuals were included in the study and grouped according to their periodontal status. Demographic data and oral health-related behavioral characteristics were evaluated. Clinical periodontal parameters and OHIP-14 scores were recorded before treatment and at the sixth week after treatment. All collected data were analyzed statistically. The study aims to determine the relationship between periodontal treatment outcomes and oral health-related quality of life in individuals with hemophilia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults aged 18 to 64 years.
- •Diagnosis of hemophilia A or hemophilia B (hemophilia group) or systemically healthy individuals/individuals with medically controlled systemic disease (control group).
- •Presence of at least 20 natural teeth, excluding third molars and teeth with orthodontic appliances.
- •Ability to provide written informed consent.
- •Willingness and ability to comply with study procedures
排除标准
- •Presence of bleeding disorders other than hemophilia A or B.
- •Uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus or uncontrolled hypertension).
- •Use of medications known to affect periodontal tissues (e.g., calcium channel blockers, anticonvulsants, or immunosuppressive agents).
- •Fewer than 20 natural teeth.
- •Inability or unwillingness to provide informed consent or comply with study procedures.
结局指标
主要结局
Oral Health-Related Quality of Life (OHIP-14) Score
时间窗: Baseline and 6 weeks after treatment
Change in Oral Health Impact Profile-14 (OHIP-14) score from baseline to 6 weeks after non-surgical periodontal treatment. Higher scores indicate poorer oral health-related quality of life.
次要结局
- Gingival Index (GI)(Baseline and 6 weeks after treatment)
- Plaque Index (PI)(Baseline and 6 weeks after treatment)
- Bleeding on Probing (BOP)(Baseline and 6 weeks after treatment)
- Probing Pocket Depth (PPD)(Baseline and 6 weeks after treatment)
- Clinical Attachment Level (CAL)(Baseline and 6 weeks after treatment)
研究者
BURAK ALEMDAĞ
Assistant Professor
Karadeniz Technical University