RESTORE-ZG: Return of Effective Spontaneous Circulation Resuscitation Evaluation Canton of Zug
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Return of spontaneous circulation (ROSC) at hospital handover
研究概览
简要总结
This study looked at cardiac arrest that happens outside a hospital. Cardiac arrest means the heart suddenly stops pumping blood. When this happens, a person collapses and needs help right away.
The study looked at care given by the emergency medical service of the Canton of Zug in Switzerland. The main goal was to learn what makes it more likely that the heart starts to pump blood again on its own. Doctors call this return of spontaneous circulation (ROSC). The researchers also wanted to describe how well the service performed over four years.
The researchers did not test any new treatment. They did not contact any people. Instead, they reviewed records that the service already had, from the years 2022 to 2025. All records were coded so that no person could be identified.
The study included 240 people who were treated for cardiac arrest. In about 4 out of 10 people (43 out of 100, or 43%), the heart started to pump blood again during care.
The researchers checked whether some factors were linked to this result. These factors were:
the heart rhythm found at the start of care how quickly the ambulance reached the person whether someone saw the person collapse whether a bystander or an emergency call handler started cardiopulmonary resuscitation (CPR), which is chest compressions and rescue breaths whether a paramedic or a doctor led the care
The heart rhythm at the start was the factor most strongly linked to the heart starting again. The result was similar whether a specially trained paramedic or a doctor led the care.
The researchers also wanted to know how well these factors can predict whether the heart will start again. They built two simple tools to estimate the chance of this result. One tool uses information known during the emergency call. The other tool uses information known when the ambulance team arrives. They tested how well the tools worked, and they compared the second tool with a tool that already exists. These tools are early versions. They need to be tested on new patients before they can be used in care.
The researchers also looked at whether the result differed by place within the service area and whether it changed over the four years.
This study cannot show that one factor causes another. It looked back at past records from one service, so the results may not apply to other places. The study did not follow people after they reached the hospital, so it does not report longer term survival. The findings can help the service review its own care and plan future work.
详细描述
This study looked at cardiac arrest that happens outside a hospital. Cardiac arrest means the heart suddenly stops pumping blood. When this happens, a person collapses and needs help right away.
The study looked at care given by the emergency medical service of the Canton of Zug in Switzerland. The main goal was to learn what makes it more likely that the heart starts to pump blood again on its own. Doctors call this return of spontaneous circulation (ROSC). The researchers also wanted to describe how well the service performed over four years.
The researchers did not test any new treatment. They did not contact any people. Instead, they reviewed records that the service already had, from the years 2022 to 2025. All records were coded so that no person could be identified.
The study included 240 people who were treated for cardiac arrest. In about 4 out of 10 people (43 out of 100, or 43%), the heart started to pump blood again during care.
The researchers checked whether some factors were linked to this result. These factors were:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Out-of-hospital cardiac arrest with a resuscitation attempt, managed by the emergency medical service of the Canton of Zug during the observation period NACA score of 6 or 7 at the end of the mission
- •Emergency physician or critical care paramedic response as part of the mission (own service physician, REGA, Alpine Air Ambulance, or external physician response)
- •Any etiology, including traumatic and non-traumatic causes
排除标准
- •Declaration of death without a resuscitation attempt
- •Documented dissent to the further use of health-related data for research
- •Missions without usable dispatch time stamps
- •Technical duplicate mission records
研究组 & 干预措施
Resuscitation-attempted OHCA (RDZ, 2022 to 2025)
All resuscitation-attempted out-of-hospital cardiac arrest (NACA 6 or 7) managed by the emergency medical service of the Canton of Zug (RDZ) between 1 January 2022 and 31 December 2025, of any etiology including traumatic and non-traumatic causes, with critical care paramedic or emergency physician involvement. Cases were identified by full enumeration of the observation period and validated against the internal resuscitation registry.
干预措施: Prehospital resuscitation care (Other)
结局指标
主要结局
Return of spontaneous circulation (ROSC) at hospital handover
时间窗: From the emergency call to the end of prehospital resuscitation on scene (return of spontaneous circulation achieved and hospitalized, or resuscitation terminated on scene), up to approximately 2 hours
Proportion of participants achieving ROSC, operationalised through the National Advisory Committee for Aeronautics (NACA) score as NACA 6 (ROSC achieved, transported with circulation) versus NACA 7 (death at the scene without sustained circulation).
次要结局
- Response-time threshold associated with ROSC(From the emergency call to the end of prehospital resuscitation on scene (return of spontaneous circulation achieved and hospitalized, or resuscitation terminated on scene), up to approximately 1 hour)
- ROSC rate by attending qualification (critical care paramedic versus emergency physician)(From the emergency call to the end of prehospital resuscitation on scene (return of spontaneous circulation achieved and hospitalized, or resuscitation terminated on scene), up to approximately 1 hour)
- Discrimination of the RESTORE-ZG On-Scene Score(From the emergency call to the end of prehospital resuscitation on scene (return of spontaneous circulation achieved, or resuscitation terminated on scene), up to approximately 1 hour)
- Geographic distribution of ROSC rate and response time(From the emergency call to the end of prehospital resuscitation on scene (return of spontaneous circulation achieved, or resuscitation terminated on scene), up to approximately 1 hour)
研究者
Felix Brinkmann
CCP-C, TP-C, MBA
Rettungsdienst Zug
