Vitamin D Supplementation in Combination With Azithromycin and Topical Retinoid for Acne: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 58
- 试验地点
- 2
- 主要终点
- Efficacious
研究概览
简要总结
The goal of this clinical trial is to compare in acne vulgaris patients. The main question it aims to answer is:
• To assess the therapeutic benefit of vitamin D supplement in acne vulgaris treatment, following a 2-month treatment regimen that includes vitamin D supplementation compared to conventional (systemic azithromycin and topical retinoid) treatment alone.
Participants will receive vitamin D supplements in addition to capsule Azithromycin and topical retinoid.
Researchers will compare groups to determine efficacy of Vitamin D supplements in the treatment of Acne vulgaris.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 13 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individuals aged between 13 and 40 years with diagnoses of Acne vulgaris are included.
排除标准
- •Individuals currently undergoing treatment for polycystic ovary syndrome (PCOs)
- •Those with obesity
- •Individuals employing vitamin supplementation
- •Those under the influence of topical or systemic steroids and acne treatment in the last 2 months.
研究组 & 干预措施
Vitamin D
干预措施: D Max Drops (Dietary Supplement)
Vitamin D
干预措施: Azithromycin 250 milligram Oral Capsule (Drug)
Placebo
干预措施: Azithromycin 250 milligram Oral Capsule (Drug)
Vitamin D
干预措施: Adapalene (Drug)
Placebo
干预措施: Adapalene (Drug)
结局指标
主要结局
Efficacious
时间窗: 2 months
Improvement in Global Acne Grading System Score from baseline to after 2 months of treatment
次要结局
未报告次要终点
研究者
Aqsa Naheed
Professor, MBBS, FCPS
HITEC-Institute of Medical Sciences