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临床试验/ISRCTN50142780
ISRCTN50142780已完成未知

Can changes in central venous oxygen saturation and central venous - arterial partial pressure of carbon dioxide difference predict changes in stroke volume in high risk surgical patients?

James Cook University Hospital (UK)0 个研究点目标入组 25 人开始时间: 2012年1月24日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
25

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • 1. Elective major open abdominal surgery (gastrointestinal, urological, gynaecological or vascular procedures with an expected duration of at least 90 minutes)
  • 2. Requirement for invasive haemodynamic monitoring including arterial and central venous blood pressure and CO measurement
  • 3. More than 50 years of age and at least one of the following:
  • 3.1. Renal impairment (serum creatinine > 130 µmol/l)
  • 3.2. Diabetes mellitus
  • 3.3. Aged 65 years and over
  • 3.4. Presence of a risk factor for cardiac or respiratory disease:
  • 3.4.1. Exercise tolerance = 6 metabolic equivalents (MET?s)
  • 3.4.2. Anaerobic threshold = 14 ml/kg/min
  • 3.4.3. Past medical history of ischaemic heart disease
  • 3.4.4. Heart failure
  • 3.4.5. Moderate or severe valvular disease
  • 3.4.6. Chronic obstructive pulmonary disease (COPD)
  • 3.4.7. Radiographically confirmed chronic lung disease (COPD, fibrosis)

排除标准

  • 1. No consent
  • 2. Pregnancy
  • 3. Emergency surgery
  • 4. Vascular surgery involving aortic cross clamping
  • 5. Allergy to Gelofusin® and Volulyte®
  • 6. Laparoscopic surgery

研究者

发起方
James Cook University Hospital (UK)

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