The Impact of Thumb Carpometacarpal Osteoarthritis on General Health
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 188
- 试验地点
- 1
- 主要终点
- Hand Function
研究概览
简要总结
This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient.
详细描述
This study is designed to define the impact of thumb arthritis on patient's general health. As a secondary objective, data will be analyzed to determine the effects of medical and musculoskeletal comorbidities on the rating of upper extremity function by the patient.
Potential Contribution: The data that we intend to gather could further our understanding of the overall health impact of thumb osteoarthritis and allow surgeons to more accurately interpret patient-rated measures of upper extremity function in the presence of comorbidities.
Osteoarthritis of the thumb carpometacarpal joint is one of the most common sites of arthritic degeneration in the hand. To date, no study has examined this conditions impact on overall health using a validated health measure (e.g. SF-36). Additionally, no study has examined the impact of medical and musculoskeletal comorbidities on patient-rated measures of upper extremity function in these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy adults clinically diagnosed with thumb carpometacarpal osteoarthritis. The diagnosis must have been confirmed radiographically prior to consideration for study enrollment.
- •Adults accompanying patients to participating offices will be recruited to be control subjects. They must not be receiving medical or surgical treatment for a hand or wrist complaint.
- •Additionally control subjects must not have been diagnosed with thumb osteoarthritis.
排除标准
- •Subjects must be over 18 years of age and English speaking.
- •Subjects are not to include incarcerated adults or those unable to provide consent for study participation.
- •Patients diagnosed with currently symptomatic hand or wrist pathology outside of the thumb carpometacarpal joint will be excluded.
- •Patient with prior surgery on the affected thumb will be excluded.
- •Pregnant females are excluded from study participation with pregnancy determined by patient self-reporting (standard of care before office radiographs).
结局指标
主要结局
Hand Function
时间窗: Baseline
Use of hand by Michigan Hand Questionnaire
次要结局
- Overall Health(Baseline)
研究者
Ryan Calfee, MD
Associate Professor of Orthopaedic Surgery
Washington University School of Medicine