Evaluation of non-invasive automatic measurement protocol for dry eye diagnosis in patients with dry eye disease and control subjects

uzerner Kantonsspital0 个研究点目标入组 75 人开始时间: 2020年12月24日最近更新: 2024年1月15日

适应症

试验速览

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35543570/ (added 29/06/2022)

•All participants:
•1. Aged between 18 and 79 years
•2. Given consent and signed the consent form declaration
•1. Ocular Surface Disease Index (OSDI©) score =13
•2. At least one of the following:
•2.1. Image result for tear break-up time (TBUT) of =10 sec
•2.2. Corneal staining grading =grade II
•2.3. Schirmer test =10 mm in 5 min
•Control subjects:
•1. OSDI© score <13
•2. Absence of sensitivity to light, ocular grittiness, ocular pain or soreness, blurred vision, poor vision, and eye redness

•1. Eyelid deformities or eyelid motility disorders (such as incomplete lid closure, entropium, ectropium, hordeola, or chalazia)
•2. Previous ocular disease leaving sequelae or requiring current topical eye therapy
•3. Active ocular allergy
•4. Known hypersensitivity to sodium fluorescein or oxybuprocaine
•5. LASIK or PRK surgery performed
•6. Punctal plugs or cauterization within the past 30 days
•7. Abormality of nasolacrimal drainage
•8. Pregnancy or lactation
•9. Systemic disease known to affect tear production or loss, diagnosed or being instable within the past 30 days
•10. Started or changed dose of chronic systemic medication known to affect tear production within the past 30 days
•11. Any eye drops within the past 8 h
•12. Contact lens worn within the past 8 h

发起方

uzerner Kantonsspital