Non-interventional Open Single Arm, Multicentre Study to Observe the Use of Preotact in Patients With Severe Postmenopausal Osteoporosis

The objectives of the study are

• to describe the quality of life at the beginning of the Preotact® treatment and at the end of the observational period (Qualeffo-41 questionnaire)
• pain assessment at the beginning of the Preotact® treatment and at the end of the observational period (VAS score)
• to describe bone mineral density at the beginning of the Preotact® treatment and at the end of the observational period (T-Score)
• to describe incidence of bone fractures caused by osteoporosis as well as of other pathological findings of the skeleton after the beginning of the Preotact® treatment
• to describe serum level of calcium and the bone resorption marker desoxypyridinoline (DPD) and N- respectively C-terminal crosslink-telopeptide (CTX and NTX) at the beginning of the Preotact® treatment and at the end of the observational period (only in subgroup of patients, where the physician sees a need to measure these parameters)
• to document all adverse drug reactions after the beginning of the Preotact® treatment
• the analysis of subgroups with different risk for bone fractures caused by osteoporosis at the beginning of the Preotact® treatment
• to assess the manageability and functioning of the Pen system for injection of Preotact® (self administered questionnaire)