NCT01221909Unknown不适用
Single Dose Tranexamic Acid for Dacryocystorhinostomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Duration of DCR surgery in minutes and amount of blood loss in milliliters during surgery.
研究概览
简要总结
Single dose tranexamic acid (TA) before dacryocystorhinostomy (DCR) operation: a prospective, double blind, placebo controlled study.
The study hypothesis: TA in DCR might reduce the intraoperative and postoperative bleeding in DCR surgery, and might reduce the duration of the surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •obstruction of nasolacrimal pathway
- •eligible for DCR surgery
- •18 years of age or older
排除标准
- •warfarin treatment
- •renal insufficiency
- •pregnancy
- •mental retardation
- •tendency to bleed
- •thromboembolic disease
- •thrombophilia
研究组 & 干预措施
Tranexamic acid single dose of 500mg
Experimental
干预措施: Tranexamic acid (Drug)
Saline
Placebo Comparator
干预措施: saline solution (Drug)
结局指标
主要结局
Duration of DCR surgery in minutes and amount of blood loss in milliliters during surgery.
时间窗: Blood loss will be measured at the end of DCR operation from the suction bowel. Duration of surgery will be caculated by registering time of operation start and end.
次要结局
- Late onset postoperative epistaxis or periorbital hematoma(8 days)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic DacryocystitisDacryocystorhinostomyHydroxybutyl ChitosanFluorouracilChronic DacryocystitisNCT06175676Tianjin Medical University Eye Hospital90
已完成
2 期
se of tranexamic acid for the prevention of blood loss in cesarean delivery: the EPTAC trialObstetric haemorrhagePregnancy and ChildbirthISRCTN11204890Irrua Specialist Teaching Hospital208
已完成
4 期
Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta StudyCesarean SectionTranexamic AcidPostpartum HemorrhagePlacenta AccretaNCT02806024University of California, San Francisco14
招募中
4 期
The safety and efficacy of silicone tube for the management of watering eyeCTRI/2009/091/000923Aurolab
已完成
不适用
aser-assisted Dacryocystorhinostomy for acquired nasolacrimal duct obstructioH04.5Stenosis and insufficiency of lacrimal passagesDRKS00012879niversitätsklinikum Köln104