Noninvasive Biomarkers for Monitoring Cardiometabolic Risk in Children
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Correlation (R values) of salivary biomarkers with blood pressure percentile and serum glucose, HDL, total cholesterol, triglyceride and insulin levels in children
研究概览
简要总结
The purpose of this study is to identify salivary biomarkers for monitoring cardiometabolic risk in children. The study hypothesis is that a combination of salivary biomarkers will predict the presence of risk factors including impaired fasting glucose, hypertension and dyslipidemia and will reflect changes in these risk factors over time.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 4 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participating in the CARDIAC Boot Camp Program
- •Between the ages of 4 and 17
- •Parental permission
- •Ability to provide assent
排除标准
- •Inability to comply with saliva collection procedures
- •Renal insufficiency or juvenile gout
结局指标
主要结局
Correlation (R values) of salivary biomarkers with blood pressure percentile and serum glucose, HDL, total cholesterol, triglyceride and insulin levels in children
时间窗: Baseline
Predictive utility (C-statistic) of salivary biomarkers for development of metabolic syndrome during childhood and adolescence
时间窗: final assessment at age 18 (up to 14 years depending on age of enrollment)
次要结局
未报告次要终点
研究者
Kristie Bridges
Associate Professor
West Virginia School of Osteopathic Medicine