Sex-unique Disparities in Survival and Resuscitation After Out-of-hospital Cardiac Arrest - a Danish Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 27,000
- 主要终点
- 30-days survival
研究概览
简要总结
The goal of this observational study is to investigate characteristics in out-of-hospital cardiac arrests (OHCA) related to sex differences.
The main questions it aims to answer are:
- are there possible differences in help provision by bystanders, cardiopulmonary resuscitation (CPR), pre-hospital treatment by emergency medical services (EMS)?
- are there differences in the presence of shockable initial rhythm (SIR) and survival rates after OHCA at successive stages of treatment? Researchers will compare all emergency medical services treated resuscitations in Denmark between 2016 and 2021 to see if there are possible differences between sexes.
详细描述
This analysis will be based on data from the national electronic based Danish OHCA registry. Data on OHCAs with resuscitative attempts in Denmark have been collected in the electronic based Danish Medical Service report system since 2016. The registry covers detailed data including the EMS report, executive entries, and advanced text searches of prehospital charts. All cases go through an elaborate validation process where all identified events are read through manually by an external verification team. This ensures high quality of data, collected according to the Utstein recommendations, throughout the approximately 5400 cases of OHCA in Denmark annually. During this verification process, supplementary sources of data are linked to each OHCA, among others information about survival, localization, initiation of bystander CPR and EMS personnel operation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All emergency medical services treated resuscitations in Denmark between 2016 and 2021
排除标准
- •Patients that are found dead at emergency medical service arrival, with sure death indicators such as rigor mortis or livores.
结局指标
主要结局
30-days survival
时间窗: 30 days from OHCA
Records on survival after 30 days from cardiac arrest
次要结局
- Return of spontaneous circulation (ROSC) at any time(2016-2021)
- Cardiopulmonary Resuscitation (CPR)(2016-2021)
- Presence of shockable initial rhythm (SIR)(2016-2021)
研究者
Eleonora Casarini
Fellow researcher and medical student
Prehospital Center, Region Zealand