The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults
试验速览
- 阶段
- 4 期
- 入组人数
- 124
- 主要终点
- To evaluate whether the fermented orange peel enzyme has the effect of reducing fat.
研究概览
简要总结
Overweight and obesity can lead to the occurrence of many chronic diseases. In addition to the body mass value (BMI), the excess body fat can also be used as criteria for assessing obesity. Citrus peels are rich in many substances including limonene, Nobiletin, 3-methoxynobiletin, and flavonoids. They could be used for lowering blood pressure and reducing blood pressure, anti-anxiety and sleep aid and etc. Fermentation technology is used to ferment the peel to increase the content of neutral components in citrus peel. Therefore, I want to evaluate whether the fermented orange peel enzyme has the effect of reducing fat.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults between the ages of 20 and 65 who are willing to sign the consent form of the subject.
- •For those with BMI ≥ 24 or fatty liver, men's body fat ≥ 25%, women's body fat ≥ 30%
- •Those who are not pregnant and are willing to cooperate with contraception during the trial period.
- •Those who have no history of cardiovascular disease, organ transplantation, epilepsy or convulsions, liver and kidney disease, malignant tumors, endocrine disease, mental disease, alcohol or drug abuse, and other major organic diseases (according to medical history).
排除标准
- •Pregnant women, people with a history of cardiovascular disease, organ transplantation, epilepsy or convulsions, liver and kidney disease, malignant tumors, endocrine diseases, mental illness, alcohol or drug abuse, and other major organic diseases (according to medical history).
- •Those who had undergone major surgery or bariatric surgery (according to medical history).
- •Currently or within 3 months before participating in the screening, those subjects used drugs that can affect body fat or increase weight significantly, such as systemic corticosteroids, tricyclic antidepressants, atypical psychiatric drugs, and mood stability Drugs (according to medical history) will be excluded.
研究组 & 干预措施
orange peel fermentation
干预措施: orange peel fermentation (Drug)
placebo
干预措施: Placebo (Drug)
结局指标
主要结局
To evaluate whether the fermented orange peel enzyme has the effect of reducing fat.
时间窗: 8 weeks
Obesity related markers
次要结局
未报告次要终点