Effect of the Administration of L-Carnitine on Body Fat Percentage and Body Weight in Overweight Women in Crossfit Training.
试验速览
- 阶段
- 2 期
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Body Fat
研究概览
简要总结
The L-carnitine has demonstrated effects in the treatment of obesity mainly promoting the fat degradation during exercise.
详细描述
A randomized, double-blind, placebo-controlled clinical trial will be carry out in 24 woman with body mass index ≥ 25 to 29.9 kg/m2. The patients will receive 1.5 g of L-Carnitine deluded in 250 ml of water or placebo before crossfit training, 5 times a week for 8 weeks. Before and after intervention the investigators evaluate: The body composition (body fat, lean body mass), arm muscle circumference, waist circumference, body weight and body mass index.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Volunteers who practice crossfit regularly (who have 3 months prior to the beginning of the study practicing crossfit).
- •Volunteers with a body mass index equal to or greater than 25 Kg/m
- •Volunteers who do not have allergies to L-Carnitine or any of its components.
- •Informed consent signed
- •Women with a recommendation of nutrition two weeks prior to the start of the study.
- •Body weight stable the last 3 months.
排除标准
- •Volunteers with pathologies such as diabetes, hypertension, metabolic syndrome and allergies.
- •Women with confirmed or suspected pregnancy.
- •Women under lactation and/or puerperium.
- •Hypersensibilility to L-Carnitine or Sucralose.
- •Kown of renal, hepatic or thyroid deseased.
- •Current or previous treatment diet (3 months before inclusion to the study).
- •Current pharmacological treatment for loose body weight or 3 months before inclusion to the study.
研究组 & 干预措施
Placebo
Sucralose 1,5 g
干预措施: Sucralose (Dietary Supplement)
L-Carnitine
L- Carnitine 1,5 g
干预措施: L-Carnitine (Drug)
结局指标
主要结局
Body Fat
时间窗: 8 weeks
Calulated by Durnin formula. Results are reported in percentage and kg
Body Weight
时间窗: 8 weeks
Subject go up onto the scale and stand still over the center of the scale with body weight evenly distributed between both feet. Omron hbf-514c an digital scale and results are reported in kg with a decimal.
Lean body mass
时间窗: 8 weeks
Calulated by Durnin formula. Results are reported in percentage and kg
次要结局
- Body Mass Index(8 weeks)
- Arm muscle circumference(8 weeks)
- Waist circumference(8 weeks)
研究者
Diana Mercedes Hernández Corona
PhD of Pharmacology
University of Guadalajara