Efficacy and Safety of 675-nm Laser for Dorsal Hand Rejuvenation in Thai Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 26
- 主要终点
- The change in pigmentation level, wrinkle and texture
研究概览
简要总结
This study aimed to evaluate efficacy and safety of 675-nm laser for dorsal hand rejuvenation in Thai patients. Twenty-six subjects aged 50 to 65 years diagnosed with wrinkle and solar lentigines on both dorsums of hands were included and treated with RedTouch for 3 times every 4 weeks. Then, they were follow up at 3 and 6 months after the final treatment. The measurement of 5-point Global Aesthetic Improvement Scale scores by physicians and subjects were conducted. Moreover, pigmentation level, wrinkle and texture were also recored using Antera. Elasticity was measured using Cutometer.
详细描述
RedTouch parameter included Moveo, power 5 W, Energy/DOT 500 mJ/DOT, then Standard, power 4 W, spacing 2000 μm, 1 pass per side.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects diagnosed with wrinkles and solar lentigines on both dorsum of hands
排除标准
- •Pregnant or lactation
- •Sugjects with a history of allergy to near-infrared wavelength or photosensitizing agents
- •Subjects who have been treated with any kind of energy-based device on both dorsum of hands 6 months prior to the inclusion
- •Subjects who have been injected with filler, or platelet-rich plasma on both dorsum of hands on their faces 6 months prior to the inclusion
- •Active skin infections
- •History of hypertrophic scars or keloids
结局指标
主要结局
The change in pigmentation level, wrinkle and texture
时间窗: Baseline, 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment
Using Antera®
次要结局
- The change in elasticity(Baseline, 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment)
- Overall improvement by physicians and patients(4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment)
- Adverse events(4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment)
- Pain score(Baseline, 4, 8, 12 weeks after the first treatment)
研究者
Woraphong Manuskiatti, M.D.
Prof. Dr.
Mahidol University