Effectiveness of customized corneal crosslinking versus standard corneal crosslinking in patients with progressive keratoconus - C-CROSS study

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 124 人开始时间: 待定最近更新: 2024年7月8日

适应症

试验速览

暂无简介。

•- age 16 to 45 years old
•- progressive keratoconus based on 1 or more of the following changes within 12
•months: (1) an increase in keratometry (Kmax, K1, K2) of 1 diopter (D) or (2)
•10% decrease of corneal thickness or (3) 1 D increase in myopia or refractive
•astigmatism

•- Corneal scarring
•- Corneal disease other than keratoconus
•- History of corneal surgery (e.g. refractive surgery, corneal transplantation,
•intracorneal ring segments)
•- Corneal thickness including epithelium less than 400 µm
•- Pregnancy
•- Among patients in whom both eyes are eligible only the first eye which is
•undergoing corneal cross-linking is enrolled in the study
•- Patient unwilling or unable to give informed consent, unwilling to accept
•randomization or inability to complete follow-up (e.g. hospital visits) or
•comply with study procedures
•- Participation in another clinical study

发起方

Medisch Universitair Ziekenhuis Maastricht