NL-OMON29263招募中不适用
‘Randomized controlled prospEctiVe trial comparing extended-release with immediate-release tacrOlimus; reducing calcineurin inhibitor related toxicity in LUng TransplantatION patients’
niversity Medical Center Groningen (UMCG)0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •For both the de novo and conversion study:
- •-Single or bilateral lung transplantation
- •-Age > 18 years
- •-On twice daily tacrolimus with stable trough levels in target range
- •-Written informed consent
- •-Participant in the TransplantLines biobank study in the UMCG
- •Additional criteria for:
- •-De novo study: De novo lung transplant patients are recruited before transplantation, and subsequently in all patients put on tacrolimus intravenously. Participants can be randomized when they are on stable daily dosage.
- •-Conversion study:
- •oAt least one year after lung transplantation with a stable clinical course, lung function and stable twice daily administered tacrolimus dosage for at least 3 months prior to conversion
- •oeGFR >30ml/min*1.73m2 calculated with the CKD-EPI formula
排除标准
- •For both the de novo and conversion study:
- •--Administration of mTOR inhibitors; everolimus, sirolimus
- •-Quadruple immunosuppression
- •-Also renal transplant recipient
- •Additional criteria for:
- •-Conversion study
- •oExpected survival < 3 years
研究者
相似试验
招募中
3 期
*Randomized controlled prospEctiVe trial comparing extended-release with immediate-release tacrOlimus; reducing calcineurin inhibitor related toxicity in LUng TransplantatION patients*NL-OMON53377Academisch Medisch Centrum145
招募中
不适用
Prospective Randomised Controlled Trial Comparing the, Early ClinicalOutcome, and Accuracy of Mechanical Alignment after Computer NavigatedTotal Knee Replacement Utilizing the Tibial cut first versus Femoral cut first.Total Knee ArthroplastyOsteoarthritisACTRN12617000767303Global Orthopaedic Technology100
已完成
不适用
Comparing the results of different skin closure techniques in children after elective surgery.ACTRN12617000158369Department of Paediatric Surgery, Monash Children's Hospital295
招募中
不适用
TKR Patient Outcomes using Wii Enhanced RehabilitatioACTRN12611000291987Jonathan Negus128
尚未招募
3 期
Sleeve Procedure vs Liraglutide vs Empagliflozin in NASH Disease and Obesity RCT (SPLENDOR)IRCT20200128046294N1Dr. Abidi Pharmaceuticals105