Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With Temporomandibular Disorders: a Randomized, Double-blind Study
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Reduction of sEMG activity of masseter muscle
研究概览
简要总结
Evaluation of myorelaxant effect of cannabis cream.compared to placebo cream in topical skin application in patients with TMD
详细描述
Cannabis sativa has a very wide application in various fields of medicine. In patients with temporomandibular disorder, especially with myofascial pain of masticatory muscles there is a special need to seek an effective pain therapy and muscle relaxing methods. Patients with TMD suffer from chronic pain and depression, cannabis topical skin application therapy seems promising in that field. Patients attending The Department of TMD in Zabrze, Polska were randomly divided into two groups: experimental and placebo. sEMG activity values were compared during 14 days therapy with cream. Positive results were obtained confirming the efficacy of the cannabis cream used in the study, compared to placebo.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
盲法说明
double blind study: for patients and researchers
入排标准
- 年龄范围
- 22 Years 至 27 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Cannabis cream
Cannabis cream topical skin application in experimental group
干预措施: Cannabis Cream (Combination Product)
Placebo cream
Placebo cream topical skin application in control group
干预措施: Placebo Cream (Combination Product)
结局指标
主要结局
Reduction of sEMG activity of masseter muscle
时间窗: 14 days
Reduction in masseter muscle electromyographic activity
次要结局
未报告次要终点
研究者
Aleksandra Nitecka-Buchta
Principal Investigator
Medical University of Silesia
