A New Era in the Treatment of Chronic Lateral Epicondylitis: Comparison of Targeted Biological Support Using a Hyaluronic Acid and Amino Acid Combination Versus Exercise Therapy: A Retrospective, Controlled Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Change in Pain Intensity (VAS)
研究概览
简要总结
This retrospective, controlled clinical study aims to evaluate the effectiveness of a targeted biological support injection containing a hyaluronic acid and amino acid combination in patients with chronic lateral epicondylitis (tennis elbow). Medical records will be reviewed to compare outcomes between patients treated in routine clinical practice with a 3-dose injection regimen (weeks 0, 2, and 4) plus a home exercise program and those treated with a home exercise program alone. Key outcome measures include pain intensity (VAS), functional status (PRTEE), grip strength, and pressure pain threshold.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged between 18 and 70 years.
- •Patients diagnosed with Lateral Epicondylitis (LE).
- •Presence of symptoms persisting for 6 weeks or longer.
- •Patients who were treated with either a 3-dose protocol of Hyaluronic Acid + Amino Acid injection combined with a home exercise program, or a home exercise program alone.
排除标准
- •History of rheumatic disease.
- •History of malignancy.
- •Presence of radiculopathy or neuropathy.
- •Presence of peripheral circulatory disorders.
- •Congenital or acquired upper extremity deformities.
- •History of coagulopathy or current use of warfarin therapy.
- •Presence of prosthesis, metal implant, or internal fixator in the elbow region.
研究组 & 干预措施
Intervention Group: HA+AA Injection + Home Exercise Program
Patients in this retrospective cohort were treated with a targeted biological support injection (Hyaluronic Acid and Amino Acid combination) administered at weeks 0, 2, and 4, in addition to the standardized home exercise program.
干预措施: Home Exercise Program (Behavioral)
Control Group: Home Exercise Program Only
Home exercise program without injection.
干预措施: Home Exercise Program (Behavioral)
Intervention Group: HA+AA Injection + Home Exercise Program
Patients in this retrospective cohort were treated with a targeted biological support injection (Hyaluronic Acid and Amino Acid combination) administered at weeks 0, 2, and 4, in addition to the standardized home exercise program.
干预措施: Hyaluronic Acid + Amino Acid Injection (Drug)
结局指标
主要结局
Change in Pain Intensity (VAS)
时间窗: Baseline, Week 4, and Month 3
Pain intensity will be measured using a 10-cm Visual Analog Scale (VAS).
次要结局
- Change in Pressure Pain Threshold (Algometry)(Baseline, Week 4, and Month 3)
- Change in Functional Status (PRTEE Score)(Baseline, Week 4, and Month 3)
- Change in Grip Strength (Hand Dynamometer)(Baseline, Week 4, and Month 3)
研究者
Serkan Polat
MD
Sivas State Hospital