Efficacy and safety of 5% nicotinamide cream in stabilizing the skin field cancerization: a randomized, double blind, placebo-controlled clinical trial

Faculdade de Medicina Julio de Mesquita Filho0 个研究点开始时间: 2023年1月20日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Sign the Free and Informed Consent Form; age over 18 years of both sexes; present at least three and at most ten lesions clinically compatible with actinic keratoses on each forearm, bilaterally.

•Actinic keratoses fewer than three or more than ten on each forearm; selected treatment area that has atypical clinical appearance or other extensive dermatoses on the forearms; presence of skin tumors in the treatment area; current and previous clinical diagnosis or evidence of any medical condition that exposes the patient to increased risks, interferes with the safety or efficacy of the proposed treatment; present hypersensitivity or allergy to any of the substances being studied; patients using any systemic or topical immunosuppressant substance and oral retinoid; immunocompromised individuals; coagulation disorders; suspected or confirmed pregnancy; women of childbearing age not using contraceptive methods; breastfeeding women; previous treatments for actinic keratoses in the last six months.

发起方

Faculdade de Medicina Julio de Mesquita Filho