A placebo-controlled, double blind study on the effect of a dopamine antagonist (Haloperidol??) on appetitive sexual conditioning in healthy female volunteers - Dopamine and classical conditioning of sexual responses

eids Universitair Medisch Centrum0 个研究点目标入组 128 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

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•female, heterosexual, no sexual complaints for at least one year, and sexually active including intercourse

•- Age < 18 or > 45 years
•- BMI < 19
•- Homosexual orientation (because of the *male* neutral stimuli)
•- Pregnancy or lactation
•- A diagnosis of affective, psychotic or substance related disorder according to DSM-IV-TR
•- Having undergone a hysterectomy or prolapse surgery
•- Using medication that may affect sexual response. To determine possible sexual side-effects the *Farmacotherapeutisch kompas* 2007 will be used.
•- Current use of psycho-pharmacological medication, or recent use (less than 4 weeks before participation) of such medication
•- Disorders of the genitals that may influence the sexual response or the measurement of the response
•- Using drugs or medication that may interfere with haloperidol (for example alcohol, or medication that influences the central nervous system).
•- A medical, and/or psychiatric illness or disorder, or a medical, and/or psychiatric history that indicates a risk in using haloperidol (for example cardiac arrhythmia, parkinson, depression, epilepsy, thyroid disorders).
•- Use of alcohol or drugs 24 hours preceding participation in the experimental session

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