NCT04127591Unknown不适用
Differential Expression and Analysis of Peripheral Plasma Exosome miRNA in Patients With Myocardial Infarction
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2019年10月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Determination of differential expression of miRNA by second-generation sequencing technology
研究概览
简要总结
The aim of this study is to determine the miRNA expression profile in peripheral blood exosomes of patients with myocardial infarction and to investigate its relationship with myocardial infarction.
详细描述
Collect exosomes in peripheral blood of patients with myocardial infarction, compare the expression of miRNA with healthy volunteers, find out the miRNAs with significant differences, and explore its relationship with the development of myocardial infarction.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age > 18 years ST elevation by ECG diagnostic of STEMI Evidency of coronary occlusion in coronariography Signed informed consent
排除标准
- •Patients who will undergo immediate PCI Pregnant and lactating women Patients with mental disorders Patients are using other experimental drugs; Refusal to provide informed.
结局指标
主要结局
Determination of differential expression of miRNA by second-generation sequencing technology
时间窗: Day 7
次要结局
- Diagnostic value of the differential microRNAs evaluate by qPCR in patients of myocardial infarction(Day 7)
研究者
Bin He
M.D./Ph.D.
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
研究点 (1)
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