Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- whole-body and site-specific microbiome profiles
研究概览
简要总结
Bacterial and fungal microbiota will be different between individual body sites; however, particular microbiome profiles both whole-body and site-specific will be unique to volunteers with a given parameter such as medical diagnosis, diet, medications taken, geographical area; etc.
详细描述
Specific aims:
- Identify and characterize whole-body and site-specific microbiome profiles.
- Identify phenotypic microbiome profiles unique to individual parameters such as demographics, medical diagnoses, diet; etc.
- Perform bacterial-bacterial, fungal-fungal and bacterial-fungal correlation analysis to identify potential synergistic and antagonistic species within these unique profiles.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Capable of giving informed consent.
- •Able and willing to complete all required specified study procedures
排除标准
- •Antibiotic or antifungal use whether topical or systemic in the past 2 or 4 weeks, respectively.
- •Unable and/or unwilling to complete all required study procedures.
结局指标
主要结局
whole-body and site-specific microbiome profiles
时间窗: through study completion, an average of 10 year
Identify and characterize whole-body and site-specific microbiome profiles.
bacterial-bacterial, fungal-fungal and bacterial-fungal correlation analysis
时间窗: through study completion, an average of 10 year
Perform bacterial-bacterial, fungal-fungal and bacterial-fungal correlation analysis to identify potential synergistic and antagonistic species within these unique profiles.
Phenotypic microbiome profiles unique to individual parameters
时间窗: through study completion, an average of 10 year
Identify phenotypic microbiome profiles unique to individual parameters such as demographics, medical diagnoses, diet; etc.
次要结局
未报告次要终点
研究者
Mahmoiud A. Ghannoum
Principal Investigator
University Hospitals Cleveland Medical Center