跳至主要内容
临床试验/NCT05145036
NCT05145036已完成不适用

The Effect of Tai Chi Exercise Among Elders With Sarcopenia

China Medical University Hospital1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2021年12月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
Appendicular skeletal muscle mass in kilograms

研究概览

简要总结

Sarcopenia has been defined as a disease which presented as low muscles strength, low muscle quantity or quality and low physical activity. The prevalence of sarcopenia is increasing with the age and it is also included in one of geriatric syndromes. Several criteria have been mentioned for diagnosis of sarcopenia, such as European Working Group on Sarcopenia in Older People (EWGSOP)、Foundation for the National Institutes of Health Biomarkers Consortium Sarcopenia Project (FNIH) and Asian Working Group for Sarcopenia (AWGS).

In European, the prevalence rate of sarcopenia is 9.25-18%; 5-7% Canadian and 14.4% Taiwanese elders have been diagnosed as sarcopenia, respectively. The sarcopenia has been found its relationship with adverse outcomes of fall down, fracture, disability, and death. The cytokines and decline in anabolic hormones play a role in the pathogenesis of sarcopenia. Tai Chi exercise is one of Qigong and well-popular in Chinese population, and is helpful to integration of body movements. Tai Chi exercise is less complicated and emphasized people's awareness of self-care which presented the relationship between human and nature. Tai Chi exercise could improve muscle performance, balance and have the benefit for fall down prevention in the elders and patients with frailty. Furthermore, Tai Chi has been found that it also could improve the muscle power and power strength in sarcopenic elders by team training. Furthermore, immune makers of inflammation process have been noted their diminishments by Qigong intervention.

The aim of this study is to investigate the effect of Tai Chi exercise in sarcopenic elders through practicing at home. The differences of muscles strength, muscle quantity or quality and physical activity after interventions would be recorded and analyzed. The cytokines related to the sarcopenia process would also be sampled.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Age 60 or older;
  • •With a diagnosis of sarcopenia [defined as EWGSOP-2] (6);
  • •Without planned exercise program or unplanned admission in 6 months;
  • •Could tolerate tests of muscle power and strength.

排除标准

  • •Uncontrolled diabetes mellitus;
  • •Uncontrolled cardiovascular diseases;
  • •Uncontrolled hypertension;
  • •Knee or hip prosthesis, pacemaker, fracture in the previous 6 months,
  • •Critical cognitive (MMSE<23)
  • •Mini Nutritional Assessment (MNA <17)
  • •Physical dysfunctions that could not tolerate our tests

研究组 & 干预措施

Tai Chi exercise

Active Comparator

In addition to standard of care participants will be asked to apply Tai Chi. There are 8 movements. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down. The 8 movements are: Ward-off, Rollback, Push, Press, Grab, Split, Elbow strike, and shoulder strike.

干预措施: Tai-Chi (Behavioral)

Comprehensive training

Active Comparator

In addition to standard of care participants will be asked to apply Comprehensive training. There are 3 exercises. Each session consisted of 10 minutes of warm-up, 40 minutes of Tai Chi, and 10 minutes of cool down. The 8 movements are: stretch exercise, strengthening exercise, and balance exercise.

干预措施: Comprehensive training (Behavioral)

结局指标

主要结局

Appendicular skeletal muscle mass in kilograms

时间窗: baseline

The appendicular skeletal muscle mass is evaluated by bioelectrical impedance (BIA) analysis

Change from baseline appendicular skeletal muscle mass at 8 weeks

时间窗: 8 weeks

The appendicular skeletal muscle mass is evaluated by bioelectrical impedance (BIA) analysis

Hand grip in kilograms

时间窗: 8 weeks

The muscle strength is evaluated with the hand-grip strength (kg) by dynamometer

Times Chair-stand test (5-CST) in minutes

时间窗: 8 weeks

The 5CST is evaluated by recording the total time that patient repeat 5 times stand and sit motion from chair

Hand grip in kilograms

时间窗: baseline

The muscle strength is evaluated with the hand-grip strength (kg) by dynamometer

Times Chair-stand test (5-CST) in minutes

时间窗: baseline

The 5CST is evaluated by recording the total time that patient repeat 5 times stand and sit motion from chair

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

The Effect of Tai Chi Exercise Among Elders With... | 临床试验