ISRCTN17605083已完成未知
A randomized controlled clinical study on non-surgical periodontal treatment in conjunction with 3 versus 7 days systemic administration of Amoxicillin and Metronidazole in severe chronic periodontitis patients
Department of prosthodontics, University of Medicine and Pharmacy Iuliu Hatieganu0 个研究点目标入组 102 人开始时间: 2015年6月16日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 102
研究概览
简要总结
2016 Results article in https://pubmed.ncbi.nlm.nih.gov/27027501/ (added 26/11/2021) 2017 Results article in https://pubmed.ncbi.nlm.nih.gov/28662049/ (added 10/07/2023) 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33004857/ (added 10/07/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. >30 years
- •2. Diagnosis of severe chronic periodontitis (Armitage 1999)
- •3. = 12 natural teeth
- •4. = 1 site/quadrant with pocket depth = 6mm
- •5. Full-mouth plaque scores = 25% (O`Leary 1972)
- •6. systemically healthy
- •7. No allergies for penicillin or 5-nitroimidazole derivates
排除标准
- •1. Non-surgical periodontal therapy within 12 months
- •2. Systemic/local antibiotics within the previous 3 months
- •3. Medication that could interact with amoxicilline or metronidazole
- •4. Pregnancy/lactation
研究者
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