Mayo Clinic IBD Biobank
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- Mayo Clinic
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Study Participants
研究概览
简要总结
Researchers are collecting and storing blood, stool, and urine samples and medical information to better understand Inflammatory Bowel Disease (IBD) to improve disease outcome.
详细描述
Subjects will be sent a letter detailing the proposed biobank and soliciting enrollment. Following the informed consent process, subjects will provide a blood sample (50 ml), urine sample (50 ml), and stool. The blood and urine samples will either be collected at the one of the Mayo Clinic outpatient laboratories or by a mail-out kit. Subjects will be asked to complete a questionnaire and 24-hour food recall questionnaire (completed online).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients diagnosed with inflammatory bowel disease (IBD) who are between the ages of 18 and 85 at time of study enrollment.
- •The diagnosis of IBD will be based on the standard IBD criteria including biochemical and colonoscopy screening.
- •Women with inflammatory bowel disease of childbearing potential and pregnant women will be offered enrollment because there is no risk to an unborn child in this investigation.
- •Patients between the ages of 18 and 85 without history of IBD or colon cancer.
排除标准
- •Patients with known liver disease.
- •Patients unable to provide informed consent.
- •Prisoners and institutionalized individuals.
- •Patients with a history of colorectal cancer.
研究组 & 干预措施
Inflammatory bowel disease (IBD)
Subjects with known inflammatory bowel disease will have samples collected of blood, urine and stool
干预措施: Blood Draw (Procedure)
Inflammatory bowel disease (IBD)
Subjects with known inflammatory bowel disease will have samples collected of blood, urine and stool
干预措施: Urine Collection (Procedure)
Inflammatory bowel disease (IBD)
Subjects with known inflammatory bowel disease will have samples collected of blood, urine and stool
干预措施: Stool Collection (Procedure)
Control Group
Subjects without inflammatory bowel disease (IBD) will have samples collected of blood, urine and stool
干预措施: Blood Draw (Procedure)
Control Group
Subjects without inflammatory bowel disease (IBD) will have samples collected of blood, urine and stool
干预措施: Urine Collection (Procedure)
Control Group
Subjects without inflammatory bowel disease (IBD) will have samples collected of blood, urine and stool
干预措施: Stool Collection (Procedure)
结局指标
主要结局
Study Participants
时间窗: 50 years
Total number of participants in the study
次要结局
- Urine Collection(50 years)
- Blood Collection(50 years)
- Stool Collection(50 years)
研究者
Konstantinos N. Lazaridis, M.D.
Principal Investigator
Mayo Clinic