Potassium Change in the Fluid Management System (FMS) Reservoir and Its Effect on the Plasma Potassium Concentration During Liver Transplantation Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- potassium concentration in the Fluid Management System (FMS) reservoir
研究概览
简要总结
Rapid infusion of red blood cells is known to result in hyperkalemia in the body. However, potassium concentration in the blood mixture (usually made of RBC, FFP and normal saline) in the reservoir of rapid infusion system and its effect on the plasma potassium change during rapid transfusion are unknown. This study is designed to investigate these changes while massive transfusion is performed during liver transplantation surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •preoperative anemia (hemoglobin < 10 g/dl)
- •preoperative coagulopathy
排除标准
- •children under age 18
- •low risk of intraoperative bleeding
结局指标
主要结局
potassium concentration in the Fluid Management System (FMS) reservoir
时间窗: after transfusion of 150 ml of blood mixture
During bolus transfusion (300ml) of blood mixture, blood sample is taken from the side port of infusion line of Fluid Management System (FMS) when 150 ml of blood mixture was transfused. Because the priming volume of the internal circuit is approximately 100 ml, blood sample that was taken after 150 ml transfusion represents the content in the reservoir.
次要结局
- plasma potassium of the patient(before and after transfuison of 300 ml of blood mixture)
研究者
Chul-Woo Jung
Assistant Professor
Seoul National University Hospital