CLINICAL EVALUATION OF TOPICAL SIMVASTATIN GEL FOR TREATMENT OF CHRONIC WOUNDS

Department of vascular surgery0 个研究点目标入组 35 人开始时间: 2019年12月15日最近更新: 2023年5月29日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 35

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

. On day 14 of treatment period, simvastatin treated patients showed complete healing of wounds in eight patients (44.4%), while only four patients (23.4%) showed complete wound healing in phenytoin treated patients. At the end of the treatment period (Four weeks), complete healing was evident in 13 patients (72%) of simvastatin group and 9 patients (52.9%) in phenytoin group. Patient who showed partial healing of their wounds were 4 patients (22.2%) in the study group versus 5 patients (29.4%) in the phenytoin group (positive control). Patient who showed no improvement were 2 patients (11.7%) in the phenytoin group versus no patient in the study group.

研究设计

研究类型: Interventional

入排标准

年龄范围: 45 Year(s) 至 64 Year(s)（—）
性别: All

入选标准

•?Diabetic foot ulcer, venous ulcer or post-surgery wound for more than 4 weeks.
•?Clean non healing wound for more than 4 weeks.
•?Age group 40-60 years, both male and female.

排除标准

•?Uncontrolled diabetics.
•?Presence of vascular impairment.
•?Associated co-morbidity such as hepatic and renal diseases.
•?Patients with allergy to Phenytoin or Simvastatin.
•?Infected wound.
•?Pregnant women.
•?Patient who had an unstable psychological profile.

研究者

发起方

Department of vascular surgery

相似试验

已完成

不适用

A study to know the effect of Simvastatin gel on bone formatio

CTRI/2016/11/007428KLE Society Institute of Dental Sciences20

尚未招募

2 期

The effect of simvastatin 2% ointment on bed sores

IRCT20210423051047N1Islamic Azad University104

尚未招募

1 期

topical simvastatin in diabetic foot ulcerdiabetic foot ulcer.Diabetes mellitus due to underlying condition with foot ulcerE08.621

IRCT20200325046854N3Iran University of Medical Sciences60

终止

2 期

Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal TreatmentRhinosinusitis

NCT01771198Centre hospitalier de l'Université de Montréal (CHUM)7

已完成

2 期

Effect of topical versus oral simvastatin as adjuvant therapy for treatment of patients with acne vulgarisAcne vulgaris.Acne vulgaris

IRCT201612049014N135Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences69