iVision - Development of a Game-based Therapy for Children With Cerebral Visual Impairment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Developmental Test of Visual - Motor Integration (Beery VMI)
研究概览
简要总结
The objective of the present study is to develop a therapeutic, adaptive, and enjoyable game that will be used by children with CVI between the mental age of 3 and 12 years. Such a game will be easy to use and implement by the children, their parents, and therapists.
详细描述
The aim of this project is to develop a novel and adaptive gamified visual perceptual therapy platform for children with cerebral visual impairment.
This is a multi-centered study involving multiple partners, namely KU Leuven, VUB, UGent, and a subcontracted game developer. Children and parents will take part during different phases of the research project as described in detail in the different phases below.
Phase I: Quantification of the visual profile (WP1) A quantification of the visual profile of children with CVI will be made by KU Leuven. This will be done using the results conducted at consultations at the CVI clinic at the Centre For Developmental Disabilities Leuven, Centrum Ganspoel, and the CP Reference Centre. A group of 50 children with CVI will be retrospectively recruited and results from their perceptual tests will be used to quantify their visual profile.
Phase II: Definition of user and technical requirements (WP1). A definition of user requirements for the development of the software and mini-games will be identified based on at least two focus groups involving parents and therapists. Two focus groups with parents/caretakes and therapists (one for each age group of the children) each lasting maximum three hours with a limit of 10 participants.
There is also a step involving the technical foundations and development of building blocks, but this will not involve patients, therefore it is not discussed further (WP2).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 3 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Visual perceptual deficits or diagnosed with CVI
- •Gross Motor Function Classification (GMFCS) level I-IV
- •Two age groups; 3-7 and 8-12 years of mental age
排除标准
- •mental age below 3 and above 12 years of mental age
- •severely limited motor abilities (cerebral palsy with a gross motor function classification level V)
- •severely limited or unable to express their experiences with the game due to serious speech disorders, deafness, autism
- •visual acuity of ≤ 3/10
结局指标
主要结局
Developmental Test of Visual - Motor Integration (Beery VMI)
时间窗: 20 minutes.
Beery a standardized and norm-referenced screening tool for visual-motor deficits. It includes updated norms for ages 2 through 18. The VMI helps assess to what extent children can integrate their visual and motor abilities. In addition to a copying task, the child also performs a visual perception matching task of the same constructs seen before in the copy task, and a motor coordination task, developed to assess the supplementary motor deficits. (Beery et al., 2010).
L94 Visual Perceptual Battery
时间窗: 25 minutes.
L94 is an object recognition battery for children aged 3-6 years. The test is composed of 5 computer tasks, \[visual matching (VISM), overlapping line drawings (OVERL), line drawings occluded by noise (NOISE), De Vos task (DE VOS), unconventional object views (VIEW). (Ortibus et al., 2009)
Preschool judgment of line orientation (PJLO)
时间窗: 10 minutes.
The PJLO is an extension of the Benton judgment of line orientation task and is administered to children between the age of 3.25 and 6 years. This test includes 24 items where the orientation of one or two target lines needs to be matched to 2, 4, or 11 choices (Stiers et al., 2005).
Developmental Neuropsychological Assessment (NEPSY-II-NL)
时间窗: Subtests geometric puzzles and arrows, 20 minutes.
NEPSY-II-NL is a customizable cognitive assessment tool for children aged 5 to 16 years. It assesses six domains with one integrated instrument, composed of different normed subtests. Among those, visual attention and visuospatial functions, are routinely performed in the diagnostic work up of children with (a suspicion of) CVI. (Korkman, 1998).
Test of Visual Perceptual Skills (TVPS)
时间窗: 30 minutes.
TVPS-3 is a standardized and norm-referenced task for children age 4-13 years that uses a response format suitable for all children, including those with disabilities. It includes subtasks of visual discrimination, visual memory, visual-spatial relationships, form constancy, visual sequential memory, figure ground, and visual closure (Martin et al., 2006).
Revisie Amsterdamse Kinderintelligentie Test (RAKIT)
时间窗: Subtests Hidden figures and Figure recogntion, 20 minutes.
RAKIT is a paediatric intelligence test, with reference values from a Dutch population of children 4-12.5 years of age. From this test, the subtest "Vertelplaat" is used to evaluate the ability to tell a logic story from a crowded scene, thereby evaluating object recognition, figure ground perception and scene perception (Bleichroth et al., 1987).
Relative Enjoyment Scale for Primary School Children adapted for cerebral visual impairment (RESC-CVI)
时间窗: 10 minutes
The RES-C measures enjoyment by relating it subjectively to a series of other activities which are part of the 'experience horizon' of a child using visual analogue scales (Van Looy et al., 2016)
Motion perception tasks
时间窗: 20 minutes.
Motion perception tasks measure motion-defined form, global motion coherence, motion speed, and biological motion, and can be administered to children between the age of 4 and 6 years. In motion-defined form, an object is concealed in a random dot kinematogram and the child is required to identify the image seen. In global motion coherence, the child indicates in which half of the display, left or right, a coherently moving strip forming a horizontal bar is located. In motion speed, two contours of a car are shown next to each other with moving dots inside, and the child indicates in which car the dots are moving at the highest speed. In biological motion, two dot matrices are shown, one is a human-point light walker (walking man) and the other one is a phasescrambled point-light figure, and the child should indicate the walking man (Van der Zee et al., 2019).
The Flemish cerebral visual impairment questionnaire (FCVIQ)
时间窗: 10 minutes.
The FCVIQ is a 46-item screening tool for CVI filled out by caregivers using a binary response format (yes or no). This tool screens for visual perceptual difficulties in daily life (Ortibus et al., 2011).
次要结局
- Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III-NL)(Non-verbal subtests, 45 minutes.)
- Snijders-Oomen Non-verbal intelligence test (SON-R 6-40)(60 minutes.)