NCT02924532已完成不适用
Diagnostic Value of Immediate Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy: A Retrospective Observational Study
Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2012年2月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- the presence/absence of hypoparathyroidism
研究概览
简要总结
The main objective of this study is to establish an optimal threshold Early parathormon (PTH) assay in order to exclude hypoparathyroidism , that is to say to obtain a negative predictive value of hypoparathyroidism highest possible.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients consecutively operated on between February 1, 2012 and December 1, 2013
- •Total thyroidectomy +/- lymphadenectomy
- •Respect of clinicobiological protocol presented above
- •The ( the ) patient ( e) was informed ( e) on the implementation of the study 's objectives, constraints and patient rights
- •The ( the ) patient ( e) is under ( e) at least 18 years
排除标准
- •The ( the ) patient ( e) is under guardianship, curatorship or under guard saves justice
- •It is not possible to give to ( the ) patient ( e) informed information
- •History of cervical radiotherapy
- •Previous history of dysfunction of the parathyroid glands
- •Previous history of surgery of the parathyroid glands
- •A history of kidney failure or hepatocellular
- •History of osteomalacia or Paget's disease
- •unhealed cancer antecedent
- •History of sarcoidosis
研究组 & 干预措施
Patients with total thiroidectomy
干预措施: immediate post operative bioassay of Parathyroid Hormone (Biological)
结局指标
主要结局
the presence/absence of hypoparathyroidism
时间窗: day 1
hypoparathyroidism is defined as: corrected serum calcium Day 1 \<1.90 and / or symptoms of hypocalcemia (cramps, tingling of the extremities and peri-oral) to Day 1 authenticated by a VAS score\> 3.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Immediate Postoperative Adjuvant Hormonal Treatment in High Risk Localised or Locally Advanced Prostate Cancer Patients.2 Years PSA Recurrence RateNCT01123434AstraZeneca200
已完成
不适用
Pre-Surgery Positron Emission Mammography in Patients With Newly Diagnosed Breast CancerBreast Cancer SurgeryBreast CancerNCT01241721Swedish Medical Center34
尚未招募
不适用
Intraoperative Parathyroid Hormone Monitoring to Guide Surgery in Renal hyperparathyroIdismSecondary HyperparathyroidismTertiary HyperparathyroidismNCT06542315McMaster University60
终止
2 期
Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated DonorLeukemia, Myeloid, ChronicAnemia, AplasticHodgkin DiseaseLymphomaLeukemia, Lymphocytic, ChronicLeukemia, Myelocytic, AcuteLeukemia, Lymphocytic, AcuteMyelofibrosisNCT00393380The Emmes Company, LLC13
Unknown
不适用
Is There Benefit From Early Postoperative PTH Monitoring?ThyroidPostoperative ComplicationsParathyroid DysfunctionHormone DisturbanceHypocalcemiaNCT04160637University Hospital "Sestre Milosrdnice"120