Comparison of Anti-sperm Antibody Levels in Inguinal Hernia Patients Who Undergo Totally Extra-peritoneal and Lichtenstein Repair
试验速览
- 阶段
- 不适用
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Change from baseline Anti-sperm antibody levels after inguinal hernia surgery
研究概览
简要总结
The purpose of this study is to determine and compare the possible affects of two different inguinal hernia repair technique (TEP and Lichtenstein) on serum ASA levels.
详细描述
Antisperm antibody levels are thought to be indirect indicators of spermatic duct injuries. The investigators' ultimate goal is to draw a conclusion about the effect of the type of surgery on spermatic duct integrity. The investigators are going to collect serum samples from inguinal hernia patients before and after surgery. The investigators aim to assess the effect of surgery on antisperm antibody levels of patients who undergo Licthenstein and TEP repair. Preoperative antisperm antibody levels will serve as control levels for each patient group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •to accept the terms of the randomization and all study
- •to have unilateral inguinal hernia and set for an inguinal hernia repair
- •to be a father
排除标准
- •to have any kind of autoimmune disorders
- •any kind of infertility history
- •to have a history of inguinal and/or genital surgery and/or trauma
研究组 & 干预措施
TEP group
Patients who undergo totally extraperitoneal hernia repair, TEP Repair.
干预措施: TEP Repair (Procedure)
Lichtenstein group
Patients who undergo Lichtenstein repair.
干预措施: Lichtenstein Repair (Procedure)
结局指标
主要结局
Change from baseline Anti-sperm antibody levels after inguinal hernia surgery
时间窗: Three months for each patient
Samples will be collected before hernia surgery and three months after surgery
次要结局
- Comparison of Anti-sperm antibody levels between inguinal hernia patients who have undergone laparoscopic totally extraperitoneal repair and Lichtenstein repair techniques(2 years anticipated)