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临床试验/NCT04631432
NCT04631432已完成不适用

Choice Switching and Autism

Technion, Israel Institute of Technology1 个研究点 分布在 1 个国家目标入组 114 人开始时间: 2021年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
114
试验地点
1
主要终点
Mean run size

研究概览

简要总结

The study aims to replicate and clarify a recently observed phenomenon whereby individuals with Autism Spectrum Disorder (ASD) switch between options in a repeated task to a greater extent than healthy controls do. In a meta-analysis a large effect size was found (.37) yet because the effect was noisy in different studies it was not statistically significant. The investigators seek to first examine a very large population through an Internet mediated platform. The sample size will be about the size of all of the previous studies that examined this issue together. Secondly, the investigators wish to understand the discrepancy between this choice switching phenomenon and the recorded tendency of ASD individuals to avoid changing choices. First, the investigators will administer the task in which the effect was found (the Iowa Gambling task) for a longer duration than previously and evaluate whether ASD individuals show increased choice switching in the first blocks of trials but reduced switching following more experience. Secondly, the investigators will administer an additional block of trials without feedback in which participants will not be able to go through a learning process. The investigators predict that this will reduce (and possible flip) the tendency of individuals with ASD to switch choices more often.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASD group - Diagnosed with ASD
  • Control - No ASD diagnosis: within age and education range of the ASD group.

排除标准

  • Demographics: Under 18 years of age.
  • Mental health: self reported brain injury and neurological disorder (besides autism).

结局指标

主要结局

Mean run size

时间窗: Through study completion, an average of 1 year

Number of consecutive selections from the same deck (across trials and in different blocks).

Advantageous selections

时间窗: Through study completion, an average of 1 year

Percentage of advantageous selections(across trials and in different blocks).

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof. Eldad Yechiam

Professor

Technion, Israel Institute of Technology

研究点 (1)

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