Positive and Negative Effects of Social Media Usage in Adolescent Girls
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Reward-processing disparities: Contrasting naturally cycling adolescent girls with those using combined oral contraceptives
研究概览
简要总结
The study aims to explore the effects of hormonal fluctuations throughout the menstrual cycle on social media use, brain architecture, neural reward processing and reward behavior, and affective status in adolescent girls. Additionally, it strives to compare the effects of exogenous and endogenous hormones on the above-mentioned aspects. For this purpose, the investigators will compare two main groups in the study: 1. Naturally cycling adolescent girls, 2. Adolescent girls using combined oral contraceptives. This study will combine self-report data via questionnaires, ecological data via Ecological Momentary Assessment (EMA), endocrine data via blood collection, and neural data via fMRI assessment to enhance the understanding of the neurobiological mechanisms underlying social media use in adolescent girls. Furthermore, it seeks to elucidate whether there are vulnerable periods throughout the menstrual cycle when adolescent girls are especially prone to dysfunctional social media use and help to design more specific interventions as well as therapy.
详细描述
For each participant, there is a screening session, a month-long EMA assessment and two experimental fMRI sessions are planned.
After making sure the participants fill the inclusion and exclusion criteria, the investigators will invite them to the laboratory for a screening session (T0). In this session, the participants will provide written informed consent and assent in case of those under 18 years old and written, informed consent for those who are 18 year old. Furthermore, the participants will participate in a standardized clinical interview to screen for mental disorders (Kinder-DIPS). Subsequently, they will be informed about the study details. Finally, they will fill out questionnaires about personality, depressive symptoms, anxiety symptoms, gender identity and norms, mood, loneliness, social media disorder, internet use, social support, and fear of missing out.
Naturally cycling adolescent girls will join the two fMRI measurements (T1 & T2) during the follicular and luteal phase of the menstrual cycle. Adolescent girls using combined oral contraceptives will join the first fMRI measurement during the pill intake period, and the second measurement during the break period. The fMRI sessions will comprise of filling out questionnaires, fMRI measurements, and blood collection for hormonal assessment.
Questionnaires on depressive symptoms, state anxiety, mood, gender identity, self-esteem, loneliness, fear of missing out (FOMO), social media disorder, internet use, social support and social media use will be administered through RedCap platform. This will ensure the assessment of subjective, self-report data and its changes throughout the measurement time of one month.
The sequence of fMRI measurements incudes four main parts, namely anatomical scan, resting-state scan, Effort Allocation Task (EAT), and diffusion tensor imaging (DTI). This protocol ensures the acquisition of the structural and functional data of the brain in the participants. The detailed protocol components are as follows:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 15 Years 至 18 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Between 15 and 18 years old adolescent girls
- •Body mass index(18-25kg/m2)
- •Natural menstrual cycle (between 25 to 31 days) OR use of combined oral contraceptives for at least 4 months
- •Social media use (e.g., Instagram, TikTok, Snapchat, Facebook, X, BeReal)
- •Non-smoking
- •German language fluency
- •Attending age-appropriate school
排除标准
- •Any neurological or psychiatric disease based on the standardized diagnostic interview (Kinder-DIPS)
- •Medical problems such as hormonal, metabolic, developmental or chronic diseases (e.g., congenital disorders, diabetes, dysfunctions of the thyroid, or congestive heart failure)
- •Pregnancy
- •Females who gave birth or were breastfeeding within the last year
- •Use of any other kind of steroid hormonal treatment (except combined oral contraceptives) or psychotropic treatment in the last three months
- •Females with premenstrual dysphoric disorder(PMDD)
- •Not willing to be informed about incidental fMRI findings
- •Additional exclusion criteria for fMRI:
- •Individuals with non-removable metal objects on or in the body such as cardiac pacemaker, artificial heart valve, metal prostheses, metal implants, metal splinters, etc.
- •Tattoos (if fMRI-incompatible according to expert guidelines)
- •Claustrophobia
- •Surgery less than three months ago
- •Pathological hearing or increased sensitivity to loud noises
- •Neurological disease or injury
- •Moderate or severe head injury
- •Restricted (corrected) vision
结局指标
主要结局
Reward-processing disparities: Contrasting naturally cycling adolescent girls with those using combined oral contraceptives
时间窗: Measured twice appr. 2-3 weeks apart; approx. 17 minutes each time
Possible differences between naturally cycling adolescent girls and those taking combined oral contraceptives on reward processing
Brain disparities: Contrasting naturally cycling adolescent girls with those using combined oral contraceptives
时间窗: Measured twice appr. 2-3 weeks apart; approximately 45 minutes each time]
Possible differences between naturally cycling adolescent girls and those taking combined oral contraceptives in brain function (functional activation based on BOLD effect)
Social media use disparities: Contrasting naturally cycling adolescent girls and those using combined oral contraceptives
时间窗: Measured through ecological momentary assessment every day throughout one month
Possible differences in social media use between the two groups
次要结局
- Social media use disparities: Contrasting follicular and luteal phase in naturally cycling adolescent girls(Measured through ecological momentary assessment every day throughout one month)
- Associations between personality and brain function & structure(Measured twice appr. 2-3 weeks apart; circa 45 minutes each time)
- Associations between personality and reward processing & behavior(Measured twice appr. 2-3 weeks apart; circa 17 minutes each time)
- Brain Disparities: Contrasting follicular and luteal phase in naturally cycling adolescent girls(Measured twice appr. 2-3 weeks apart; circa 45 minutes each time)
- Reward-processing disparities: Contrasting follicular and luteal phase in naturally cycling adolescent girls(Measured twice appr. 2-3 weeks apart; circa 45 minutes each time)
- Self-esteem differences: Contrasting follicular and luteal phase in naturally cycling adolescent girls(Measured through ecological momentary assessment every day throughout one month)