Comparison of post-operative cycloplegia, miotics, and no treatment after Minimally Invasive Glaucoma Surgery: A Randomized Controlled Trial.
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The change of PAS from baseline
研究概览
简要总结
Minimally Invasive Glaucoma Surgeries (MIGS) have developed in recent years. These procedures are characterized by ab-interno microincisions, minimal trauma, a high safety profile, high efficacy, and fast recovery.
Although minimally invasive glaucoma surgeries (MIGS) have made significant advancements, they are not without failures. Studies indicate that failure rates for various MIGS procedures can range from 20% to 40%. (9-11) Several factors contribute to these failures, including postoperative intraocular pressure (IOP) spikes and heightened responses to steroids. Additionally, the formation of peripheral anterior synechiae (PAS) may lead to increased IOP after surgery, which can further raise the failure rates of these procedures.
Our study aims to investigate whether the use of cycloplegic drops postoperatively, which keeps the lens-iris diaphragm positioned posteriorly, can reduce the formation of PAS and lower the failure rates in patients undergoing MIGS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 3.00 Month(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Any diagnosed case of glaucoma, undergoing MIGS during the study period.
排除标准
- •Any patient with blood dyscrasia.
结局指标
主要结局
The change of PAS from baseline
时间窗: Three months
The extent of PAS (in clock hours)
时间窗: Three months
IOP and correlation to PAS
时间窗: Three months
次要结局
- Intraocular Pressure(3 months)
- Reduction in antiglaucoma meds(3 months)
研究者
Sushmita Kaushik
Post Graduate Institute of Medical Education and Research, Chandigarh