EUCTR2006-002354-30-DE进行中（未招募）不适用
Effect of Acute Insulin Intervention followed by Pioglitazone and Metformin Treatment on Metabolic Parameters in Type 2 Diabetic Patients with inadequate Metabolic Control
Takeda Pharma GmbH0 个研究点开始时间: 2006年6月8日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1.Type 2 diabetes according to the ADA Criteria
- •2.Treatment with oral antidiabetic agents except PPAR?- agonists
- •3.Age 30-75 years
- •4.Fasting C-Peptide levels > 2 ng/mL
- •5.HbA1c >= 6.5%
- •6.more than 2 blood glucose measurements >200 mg/dL within the last two weeks
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1.Type 1 diabetes mellitus
- •2.History of ketoacidosis or lactic acidosis
- •3.Use of systemic corticosteroids within the last 3 months prior to screening visit
- •4.Anamnestic history of hypersensitivity to the study drugs or to drugs with similar chemical structures
- •5.History of severe or multiple allergies
- •6.Treatment with any other investigational drug within 3 months before trial entry.
- •7.Have had more than one unexplained episode of severe hypoglycaemia (defined as requiring assistance of another person due to disabling hypo¬glycaemia) within 6 months prior to screening visit
- •8.Progressive fatal disease
- •9.History of drug or alcohol abuse within the last 5 years prior to study participation
- •10.A history of significant cardiovascular ( NYHA stage II - IV), respiratory, gastrointestinal, hepatic (ALAT > 2.5 times the normal reference range), renal (creatinine > 1.1 mg/dL in women and > 1.5 mg/dL in men), neurological, psychiatric and/or haematological disease as judged by the investigator.
- •11.Blood donation within the last 30 days
- •12.Pregnancy or breast feeding
- •13.Sexually active women of childbearing age not consistently and correctly practicing birth control by implants, injectables, combined oral contraceptives, hormonal intrauterine devices (IUDs), sexual abstinence or vasectomised partner.
- •14.Lack of compliance or other similar reason, that, the investigator believes, precludes satisfactory participation in the study
- •15.Pre-treatment with PPAR? agonists within the 3 months prior to screening
- •16.Respiratory insufficiency
- •17.Myocardial infarction within 6 months prior to screening visit
研究者
相似试验
进行中（未招募）
不适用
Effect of prandial treatment with insulin VIAjectTM compared to regular human insulin and insulin lispro on postprandial endothelial function and microvascular stress in type 2 diabetic patientsMedDRA version: 9.1Level: LLTClassification code 10045242Term: Type II diabetes mellitusType 2 Diabetes MellitusEUCTR2008-001184-11-DEBiodel Inc
进行中（未招募）
不适用
Effekt av insulininfusion på sjukdomsförloppet vid infekterade fotsår samt vid thorax- och kärlkirurgi hos patienter med diabetesdiabetes mellitus infekterat fotsårkärl eller thoraxkirurgisk operationMedDRA version: 9.1Level: LLTClassification code 10012664Term: Diabetic foot ulcerMedDRA version: 9.1Level: LLTClassification code 10011090Term: Coronary artery surgeryMedDRA version: 9.1Level: LLTClassification code 10012601Term: Diabetes mellitusMedDRA version: 12.0Level: LLTClassification code 10048038Term: Wound infectionEUCTR2008-004537-19-SEKarolinska Universitetssjukhuset
已完成
不适用
The effect of rapid-acting insulin injected by needle-free jet-injection in the management of hyperglycemia in patients with diabetes10018424diabetesNL-OMON38926niversitair Medisch Centrum Sint Radboud20
终止
不适用
The acute effects of resistance exercise on insulin sensitvity.Type 2 diabetes and non-diabetic individualsMetabolic and Endocrine - DiabetesACTRN12608000289314RMIT University56
进行中（未招募）
不适用
Effect of Prandial Treatment with Insulin Glulisine compared to Regular Human Insulin on Postprandial Endothelial Function and Microvascular Stress in Type 2 Diabetic Patients - Insulin glulisine and postprandial vascular functioEUCTR2006-005127-42-DEInstitut für Klinische Forschung und Entwicklung (ikfe) GmbH