NCT06362304招募中不适用
Application of 99mTc-CNDG SPECT/CT Imaging in the Diagnosis of Brain Tumors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- SUVmax
研究概览
简要总结
The goal of this clinical trial is to evaluate the value of 99mTc-CNDG for diagnosis of brain tumors by comparing it with 18F-FDG-PET. The main questions it aims to answer are:
- What is the diagnostic consistency between 99mTc-CNDG and 18F-FDG?
- What is the correlation between the SUVmax value of 99mTc-CNDG and tumor type?
Participants will:
Receive18F-FDG-PET and 99mTc-CNDG examination within 2 weeks before surgery. Obtain pathological diagnosis by surgery or biopsy as the gold standard.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with clinical diagnosis of brain tumor;
- •Be at least 18 years old;
- •The final pathological results could be obtained by surgery or biopsy;
- •Informed consent and the ability to be followed up;
- •Those who did not meet the exclusion criteria.
排除标准
- •Insulin-dependent diabetes mellitus or fasting blood glucose >7 mmol/L before 99mTc-CNDG injection;
- •Severe liver or kidney disease (serum creatinine level >3.0mg/dL or any liver enzyme level ≥ 5 times the upper limit of normal);
- •Severe hypersensitivity or hypersensitivity to radiocontrast agents;
- •Claustrophobia (inability to undergo SPECT/CT or PET/CT scans);
- •Patients receiving radiotherapy and chemotherapy;
- •Being pregnant or breastfeeding.
结局指标
主要结局
SUVmax
时间窗: 1month
1\. Diagnostic consistency evaluation of 99mTc-CNDG and 18F-FDG; 2.Correlation of SUV value of 99mTc-CNDGwith tumor type
次要结局
未报告次要终点
研究者
研究点 (1)
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