Key Technology Research of the Comprehensive Treatment of Multiple Organ Dysfunction Syndrome
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1
- 试验地点
- 1
- 主要终点
- the prognostic assessment of aged patients with MODS
研究概览
简要总结
The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age > 60 years old;
- •presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention;
- •have trachea intubation after admitting to intensive care unit within 24 hours.
排除标准
- •end stage multiple organ failure.
结局指标
主要结局
the prognostic assessment of aged patients with MODS
时间窗: 28 days
According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems \[(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)\], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.
次要结局
未报告次要终点
研究者
Kun Xiao
Key Technology Research of the comprehensive treatment of Multiple organ dysfunction syndrome
Chinese PLA General Hospital