NCT00715065撤回不适用
Neuroimaging in Blood Phobia Syncope
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- fMRI BOLD signal
研究概览
简要总结
We plan to study patient who faint in response to the sight of blood and compare them to healthy subjects who do not. We are going to use a special type of MRI scan (functional MRI) to determine if there are differences in brain activation in response to seeing bloody or gory pictures that occur before the fainting occurs.
详细描述
Another aim of the study is to determine whether or not differences in personality traits among people with blood phobia is associated with differences in BOLD signal responses during fMRI.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 years of age
- •History of at least one syncopal episode upon exposure to viewing blood (Case Group)
- •Negative urine pregnancy test on study day
排除标准
- •Vasoactive medications (within 2 weeks of study day)
- •antihypertensives
- •beta blockers
- •vasoconstrictors
- •Psychotropic medications (within 4 weeks of study day)
- •History of psychostimulant or opiate use
- •History of alcohol, benzodiazepine or cannabis abuse or dependence
结局指标
主要结局
fMRI BOLD signal
时间窗: Immediate
次要结局
- Disgust Scale (Revised)(Single Visit)
- Blood Injection Symptoms Scale(Single visit)
研究者
Satish R. Raj
Assistant Professor
Vanderbilt University
研究点 (1)
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