A Single-Center Retrospective Cohort Study Evaluating the Management and Outcomes of Pediatric Pancreatic Duct Stones Using Endoscopic and Surgical Techniques
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 主要终点
- stone clearance
研究概览
简要总结
The goal of this observational study is to evaluate the long-term effects of ERCP and surgery in pediatric patients with pancreatic duct stones. The main objective is to determine the optimal treatment choice(ERCP or surgery) for children with pancreatic duct stones and identify the appropriate timing for surgery in patients who have undergone multiple ERCP procedures, in order to avoid adverse outcomes caused by repeated trauma to the duodenal papilla.
Last updated on January 24, 2025.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 2 Months 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 0 to 18 years
- •Diagnosed with pancreatic duct stones by imaging (e.g., ultrasound, CT, MRCP)
- •Treated and followed at pediatric surgery, west china hospital, between 2014 and 2025
- •Complete clinical data available for review
排除标准
- •Pancreatic duct stones secondary to previous pancreatic or biliary surgery
- •Concurrent severe systemic diseases (e.g., advanced cardiac, renal, or hepatic disease)
- •Incomplete or missing key clinical records
结局指标
主要结局
stone clearance
时间窗: From intervention to the end of treatment at 1 week
The stone clearance rate refers to the proportion of patients confirmed by postoperative imaging (MRCP) to have no residual pancreatic duct stones.
complication rate
时间窗: From enrollment to the end of treatment at 2 weeks
The complication rate refers to the incidence of pancreatitis following ERCP and associated procedures, as well as pancreatic fistula, bile leakage, and the necessity for prolonged drainage after the Frey procedure.
reintervention rate
时间窗: From enrollment to the end of treatment at 1 year.
The reintervention rate refers to the proportion of patients who required additional invasive procedures (either ERCP or surgery) after the initial treatment.
次要结局
未报告次要终点
研究者
Yifan Deng
M.Med
West China Second University Hospital