The efficacy of topical phenytoin ointment on healing venous leg ulcers: a randomized double blind placebo controlled trial

Department of Pharmacology0 个研究点开始时间: 待定最近更新: 2024年8月20日

适应症

试验速览

暂无简介。

•1. Male and female patients above 18 years with a single lower limb venous ulcer
•2. Area of ulcer more than 4 cm2 and less than 25cm2
•3. Duration of the ulcer less than 8 weeks
•4. Duplex scan evidence of venous insufficiency demonstrated

•1. Patients who have the following comorbidities:
•a. Occlusive arterial disease – Ankle Brachial Pressure Index (ABPI) below 0.9
•b. Uncontrolled diabetes mellitus with HbA1c > 8% or > 3 or more fasting blood glucose values in
•the last 6 months > 250mg/dl
•c. Chronic kidney disease Stage III and above
•d. Diagnosed chronic liver disease
•e. Heart failure NYHA class 3 or 4
•f. Diagnosed Vasculitis
•g. Anemia with Hb less than 10g/dL
•2. Recent (< 6 months) varicose vein surgery, laser ablation or sclerotherapy
•3. Ulcers with infection/cellulitis/ osteomyelitis
•4. Current smokers
•5. Patients with history of allergy to phenytoin
•6. Patients with epilepsy who are on oral phenytoin

发起方