Implementation of LUCAS 2 in Helicopter Rescue in South Tyrol
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Time from arrival of rescue team to start of mechanical compressions
研究概览
简要总结
Cardiopulmonary resuscitation (CPR) is used to maintain adequate perfusion of vital organs in cardiac arrest patients and is fundamental for the neurological outcome and survival of these individuals. Unfortunately, the quality of CPR may be inadequate due largely to ineffective chest compressions resulting from rescuer fatigue and interruptions in compressions. The LUCAS device (Lund University Cardiopulmonary Assist System, Jolife, Lund, Sweden), introduced in 2002, is the most extensively tested and applied automated alternative to manual CPR for in-hospital care of cardiac arrest patients and during ambulance transfer; the feasibility of application of this device in helicopter emergency medical service (HEMS) operations, however, has never been addressed. The objective of this project is to equip the three active rescue helicopters in South Tyrol with the LUCAS 2 mechanical chest compression device to answer the question: What is the feasibility and efficiency of using this device for prolonged CPR in cardiac arrest patients requiring CPR during HEMS rescue operations and transport?
详细描述
This is a non-controlled, observational study. Physiological endpoints: MAP (mean arterial pressure); etCO2 (end-tidal expiratory pCO2); ROSC (return of spontaneous circulation); PaO2 (arterial pO2); PaCO2 (arterial pCO2); endpoints to assess feasibility: time from arrival to start of mechanical compressions, problems during transfer into the helicopter and in-field manoeuvers, problems with application of device, problems with patient transfer to hospital premises, hands-off time, personnel requirements.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cardiac arrest with indication of CPR
- •informed consent for those regaining legal competence
排除标准
- •declaration of death on site
- •contraindications of using the device
- •age <18 y
结局指标
主要结局
Time from arrival of rescue team to start of mechanical compressions
时间窗: assessed immediatly after the operation is concluded
Presence of abdominal or thoracic lesions caused by automated chest compressor
时间窗: Assessed at clinical examination during hospital stay (day 1 to day 30) or autopsy
次要结局
- End-tidal expiratory pCO2(At hospital arrival (expected between 5 minutes and 1 hour from start CPR))
- Arterial pCO2(At hospital arrival (expected between 5 minutes and 1 hour from start CPR))
- Mean arterial pressure(At hospital arrival (expected between 5 minutes and 1 hour from start CPR))
- Return of spontaneous circulation(Could be each moment during CPR)
- Arterial pO2(At hospital arrival (expected between 5 minutes and 1 hour from start CPR))